Evidence map›Paper›PMID 41542532›Full record

ArticlebioRxiv : the preprint server for biology2026

Lauren B Horowitz, Olya Yarychkivska, Yun Lu, Shai Shaham

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauren B HorowitzLaboratory of Developmental Genetics, The Rockefeller University, New York, NY 10065, USA.ORCID 0000-0003-0385-7555
Olya YarychkivskaLaboratory of Developmental Genetics, The Rockefeller University, New York, NY 10065, USA.
Yun LuLaboratory of Developmental Genetics, The Rockefeller University, New York, NY 10065, USA.
Shai ShahamLaboratory of Developmental Genetics, The Rockefeller University, New York, NY 10065, USA.ORCID 0000-0002-3751-975X

Funding

Glial Control of Neuron Development and Function - Administrative SupplementR35NS105094 · NINDS · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2018 to 2025
$8.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Linker cell death regulation in C. elegansR01HD103610 · NICHD · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2021 to 2025
$1.8M
Death and Destruction: How the Ubiquitin Proteasome System Executes Linker Cell-type DeathF32GM145036 · NIGMS · ROCKEFELLER UNIVERSITY · PI HOROWITZ, LAUREN BAYER · 2022 to 2023
$144k
NICHD NIH HHS R01 HD103610NIGMS NIH HHS F32 GM145036NIH HHS P40 OD010440NINDS NIH HHS R35 NS105094
6 · The paper itself

Abstract

Programmed cell death is essential for animal development and homeostasis, and its disruption accompanies many human disorders. Linker cell-type death (LCD) is a morphologically conserved non-apoptotic developmental cell death program with features resembling polyglutamine-dependent neurodegeneration. In

Indexed as

C. elegansEBAX-1LCDlinker cell-type deathnon-apoptotic cell deathProgrammed cell deathTarget Directed miRNA DegradationUbiquitin Proteasome SystemZSWIM8

Identifiers

PMID41542532
PMCPMC12803083

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.