Evidence map›Paper›PMID 41542524›Full record

ArticlebioRxiv : the preprint server for biology2025

Active maintenance of meiosis-specific chromosome structures in

Liesl G Strand, Charlotte P Choi, Savannah McCoy, Emmanuel T Nsamba, Nicola Silva, Anne M Villeneuve

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Liesl G StrandDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-0602-4591
Charlotte P ChoiDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-3649-6290
Savannah McCoyDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, California, USA.
Emmanuel T NsambaDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-1626-1868
Nicola SilvaDepartment of Biology, Masaryk University, Faculty of Medicine, Brno, Czech Republic.ORCID 0000-0001-5406-2280
Anne M VilleneuveDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-5193-2076

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI MICHAEL KENNEY · 2007 to 2026
$71.4M
GENETICS TRAINING PROGRAM FOR PHD CANDIDATEST32GM007790 · NIGMS · STANFORD UNIVERSITY · PI BRUNET, ANNE, KINGSLEY, DAVID M · 1985 to 2020
$12.8M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Meiotic Chromosome Inheritance in C. elegansR35GM126964 · NIGMS · STANFORD UNIVERSITY · PI ANNE M VILLENEUVE · 2018 to 2026
$6.2M
NCI NIH HHS P30 CA124435NIGMS NIH HHS R35 GM126964NIGMS NIH HHS T32 GM007790NIH HHS P40 OD010440
6 · The paper itself

Abstract

Meiotic prophase is characterized by a dynamic program in which germ cells undergo a complex series of associations and dissociations of protein complexes that drive assembly, remodeling, and disassembly of meiosis-specific chromosome structures and dramatic changes in chromosome compaction. Failure to properly coordinate these processes can result in improper chromosome segregation, producing aneuploid gametes and inviable zygotes. Here, we investigate the roles of

Identifiers

PMID41542524
PMCPMC12802401

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.