Evidence map›Paper›PMID 41542500›Full record

ArticlebioRxiv : the preprint server for biology2026

Chromosome-specific differences in the recombination landscape of spontaneous meiotic nondisjunction.

Carolyn A Turcotte, Jeff Sekelsky

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Carolyn A TurcotteCurriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0001-6607-131X
Jeff SekelskyIntegrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-4424-677X

Funding

Mechanisms of Meiotic and Mitotic RecombinationR35GM118127 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JEFF J. SEKELSKY · 2016 to 2026
$6.0M
NRSA IN GENETICST32GM007092 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SEKELSKY, JEFF J. · 1985 to 2019
$5.9M
Mechanisms and regulation of meiotic recombination"F31AG074637 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TURCOTTE, CAROLYN ANNE · 2021 to 2023
$114k
NIA NIH HHS F31 AG074637NIGMS NIH HHS R35 GM118127NIGMS NIH HHS T32 GM007092
6 · The paper itself

Abstract

Failures in chromosome segregation during meiosis result in aneuploid gametes and are the leading cause of miscarriage. The position and number of crossovers, genetic exchanges between homologous chromosomes, are essential to their accurate disjunction in meiosis. Previous research analyzing nondisjunction of acro- and telocentric chromosomes in human and

Indexed as

crossover patterningmeiosisnondisjunctionrecombination

Identifiers

PMID41542500
PMCPMC12803044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.