ArticlebioRxiv : the preprint server for biology2026
Smoothened turnover regulated by Hedgehog signaling in Drosophila.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
During development, the processes of cell-cell signaling orchestrate growth and morphogenesis using both static features and moving parts. For example, expression domains of genes which set states of determination may be fixed in space for periods of time, but multiple signals move between the determined cells and intracellular movements of components of the signal transduction machines are key to information exchange. In the Drosophila wing imaginal disc, Hedgehog (Hh) protein produced in the posterior compartment moves to cells across the anterior/posterior compartment border to induce signal transduction and various intracellular responses. In this work, we investigated protein turnover and intracellular trafficking of components of Hh signal transduction in the wing disc and found that both are major features of Hh signaling.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.