ArticlebioRxiv : the preprint server for biology2026
Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundT helper 1 (T
methodsWe devised a reductionistic model to determine the role of IFN-γ in IL-17A-driven inflammation during
resultsIFN-γ promptly muted IL-17A-induced inflammatory cell accumulation in
conclusionsOur findings identify a distinct immunoregulatory mechanism that operates within non-lymphoid tissues, where IFN-γ limits IL-17A-mediated type 3 inflammation via STAT1. Thus, the frequent accompaniment of T
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