Evidence map›Paper›PMID 41542422›Full record

ArticlebioRxiv : the preprint server for biology2026

Bedaquiline inhibits the ATP synthase leak channel and prevents glutamate-induced neuronal death.

Amrendra Kumar, Erin Smith, Ikram Mezghani, Subhash Eedarapalli, Yangyu Wu, Khondoker Adeba Ferdous, Emma Amjad, Han-A Park, Nelli Mnatsakanyan

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Amrendra KumarDepartment of Cell and Biological Systems, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Erin SmithDepartment of Cell and Biological Systems, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Ikram MezghaniDepartment of Cell and Biological Systems, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Subhash EedarapalliDepartment of Cell and Biological Systems, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Yangyu WuDepartment of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA.
Khondoker Adeba FerdousDepartment of Human Nutrition, Hospitality and Sport Management, University of Alabama, Tuscaloosa, AL, USA.
Emma AmjadDepartment of Human Nutrition, Hospitality and Sport Management, University of Alabama, Tuscaloosa, AL, USA.
Han-A ParkDepartment of Human Nutrition, Hospitality and Sport Management, University of Alabama, Tuscaloosa, AL, USA.
Nelli MnatsakanyanDepartment of Cell and Biological Systems, Pennsylvania State University College of Medicine, Hershey, PA, USA.

Funding

Structural and functional characterization of ATP synthase c-subunit leak channel and its role in AD pathogenesisR01AG072484 · NIA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MNATSAKANYAN, NELLI · 2024 to 2025
$1.4M
NIA NIH HHS R01 AG072484
6 · The paper itself

Abstract

F

Identifiers

PMID41542422
PMCPMC12803175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.