Evidence map›Paper›PMID 41542397›Full record

ArticlebioRxiv : the preprint server for biology2026

Protocol for using an ELISA to detect total α-synuclein levels in

Marco Sciortino, Raquel Velazquez, Haven Tillmon, Swati Banerjee

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Marco SciortinoDepartment of Cellular and Integrative Physiology, University of Texas San Antonio Health Science Center, Joe R. and Teresa Lozano Long School of Medicine, San Antonio, Texas, USA.ORCID 0009-0008-4324-9953
Raquel VelazquezDepartment of Cellular and Integrative Physiology, University of Texas San Antonio Health Science Center, Joe R. and Teresa Lozano Long School of Medicine, San Antonio, Texas, USA.ORCID 0009-0004-9112-2085
Haven TillmonDepartment of Cellular and Integrative Physiology, University of Texas San Antonio Health Science Center, Joe R. and Teresa Lozano Long School of Medicine, San Antonio, Texas, USA.ORCID 0000-0001-8131-173X
Swati BanerjeeDepartment of Cellular and Integrative Physiology, University of Texas San Antonio Health Science Center, Joe R. and Teresa Lozano Long School of Medicine, San Antonio, Texas, USA.ORCID 0000-0001-8749-5197

Funding

Molecular Mechanisms of Tubulin Polymerization Promoting Protein in Mitochondrial Function and Neuronal SurvivalR01NS134867 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Swati Banerjee · 2024 to 2026
$1.2M
NINDS NIH HHS R01 NS134867
6 · The paper itself

Abstract

In Parkinson's disease (PD), aggregation of alpha-synuclein (α-syn) contributes to neuronal dysfunction and death, particularly in dopaminergic neurons, driving disease progression. Several pathogenic point mutations have been identified in human α-syn such as

Identifiers

PMID41542397
PMCPMC12803076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.