Evidence map›Paper›PMID 41542395›Full record

ArticlebioRxiv : the preprint server for biology2026

Liquid liquid phase separation of the intrinsically disordered protein JPT2 compartmentalizes components of NAADP-evoked Ca

Sushil Kumar, Gihan S Gunaratne, Jasmine Cornish, Kirsten M Silvey, Qianru Mu, Zhong Guan, Gabriella T Heller, James T Slama, Sandip Patel, Jonathan S Marchant

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sushil KumarDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.ORCID 0000-0002-1364-314X
Gihan S GunaratneDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
Jasmine CornishThe Francis Crick Institute, London, NW1 1AT, UK.
Kirsten M SilveyStructural and Molecular Biology, University College London, Gower Street, London, WC1E 6BT, UK.
Qianru MuDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.
Zhong GuanDepartment of Medicinal & Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, OH 43614, USA.
Gabriella T HellerBind Research, Apex, 1 Tribeca Walk, London, NW1 0QE.
James T SlamaDepartment of Medicinal & Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, OH 43614, USA.
Sandip PatelDepartment of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.
Jonathan S MarchantDepartment of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.ORCID 0000-0001-6592-0877

Funding

Functional architecture of IP3-evoked local Ca2+ signalsR01GM088790 · NIGMS · UNIVERSITY OF MINNESOTA · PI MARCHANT, JONATHAN S, SLAMA, JAMES T · 2009 to 2025
$4.7M
800 MHz NMR Spectrometer for Southeast WisconsinS10OD025000 · OD · MEDICAL COLLEGE OF WISCONSIN · PI VOLKMAN, BRIAN F · 2019 to 2019
$2.0M
NIGMS NIH HHS R01 GM088790NIH HHS S10 OD025000Wellcome Trust FC001029
6 · The paper itself

Abstract

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a Ca

Identifiers

PMID41542395
PMCPMC12803092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.