Evidence map›Paper›PMID 41542345›Full record

ArticleRSC advances2026

Hyaluronan like polysaccharide based nanodrugs with enhanced CD44 avidity for image-guided drug delivery to breast cancer.

Chia-Wei Yang, A K M Atique Ullah, Xuefei Huang

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chia-Wei YangDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA.
A K M Atique UllahDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA.ORCID https://orcid.org/0000-0002-4545-2663
Xuefei HuangDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA.ORCID https://orcid.org/0000-0002-6468-5526

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted drug delivery is an exciting strategy to treat cancer and reduce the harmful side effects of chemotherapy to normal tissues. CD44 has been an attractive target for drug delivery due to its expression on many types of tumor cells including breast cancer. To better target the CD44-expressing breast cancer cells, we report the design and synthesis of a new nanodrug, G2-Sal-ICG, comprising a hyaluronan (HA)-like polysaccharide (G2) conjugated with the anticancer drug salinomycin (Sal) and the imaging agent indocyanine green (ICG). This nanodrug targets CD44 receptors and allows for near-infrared fluorescence imaging (NIR-FI) to track drug delivery in real-time. G2-Sal-ICG had significantly higher affinity with CD44

Identifiers

PMID41542345
PMCPMC12801402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.