Evidence map›Paper›PMID 41542316›Full record

ReviewParasite epidemiology and control2026

Plants with promising antileishmanial activity in Colombia: A systematic review and meta-analysis.

Carlos Nieto-Clavijo, Liliana Morales, Guillermo Zambrano, Andrés Delgado-Aldana, Zayda-Lorena Corredor-Rozo, Eliana Patricia Calvo, Dario Tinjacá, Jacqueline Chaparro-Olaya

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Parasite epidemiology and control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carlos Nieto-ClavijoLaboratorio de Parasitología Molecular, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia.
Liliana MoralesLaboratorio de Parasitología Molecular, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia.
Guillermo ZambranoLaboratorio de Parasitología Molecular, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia.
Andrés Delgado-AldanaLaboratorio de Parasitología Molecular, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia.
Zayda-Lorena Corredor-RozoBacterial Molecular Genetics Laboratory, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia.
Eliana Patricia CalvoGrupo de Virología, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia.
Dario TinjacáApplied Chemistry Research Group-INQA, Pharmaceutical Chemistry Program, Universidad El Bosque, Bogotá, Colombia.
Jacqueline Chaparro-OlayaLaboratorio de Parasitología Molecular, Vicerrectoría de Investigaciones, Universidad El Bosque, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Leishmaniasis remains a global public health challenge. The exceptional biodiversity of Colombia includes numerous plants that constitute a promising resource for the development of new antileishmanial therapies. Aim of the study: To systematically assess the Materials and methods: A systematic search (2000-April 2025) of PubMed, EMBASE, and LILACS identified Results: Thirteen studies provided complete data for meta-analysis. The pooled mean IC₅₀ was 37.89 μg/mL (95 % CI: 34.99-40.78), with substantial heterogeneity (I Conclusion: Colombian plants represent a promising source of leishmanicidal agents, with several species exhibiting strong

Indexed as

Antileishmanial activityColombiaDrug discoveryEthnopharmacologyIC50Leishmaniameta-analysisPlant extractsSelectivity index

Identifiers

PMID41542316
PMCPMC12800360

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.