ArticleJournal of anaesthesiology, clinical pharmacology
Comparison of non-hypoxic apnea time in infants during induction of anesthesia with or without peep-A randomized controlled study.
Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background and Aims: Infants are at the highest risk of oxygen desaturation during induction of anesthesia owing to their distinct anatomical and physiological characteristics. Prolongation of non-hypoxic safe apnea time by use of positive end expiratory pressure (PEEP) during induction has been studied extensively in adults. Although few studies have been conducted in infants, they lacked methodological rigor. Hence, we designed a scientifically rigorous study aimed at investigating the effects of application of PEEP during induction of anesthesia on the duration of non-hypoxic apnea time in infants. Material and Methods: Seventy-two infants were induced as per institutional protocol and mechanically ventilated for three minutes with volume-controlled ventilation and set ventilator parameters with PEEP of either 7 cm H Results: The duration of non-hypoxic apnea time was significantly longer in the PEEP group (n = 33) as compared to the control group (n = 33); 122 s (IQR = 52) vs. 95 s (IQR = 27) ( Conclusions: Addition of PEEP of 7 cmH
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