Evidence map›Paper›PMID 41542203›Full record

ArticleJournal of anaesthesiology, clinical pharmacology

Effect of low tidal volume ventilation on cerebral hemodynamics in patients with severe traumatic brain injury.

Nipun Gupta, Ashish Bindra, Amiy Verma, Saurav Singh, Surya K Dube

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nipun GuptaNeuroanaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
Ashish BindraNeuroanaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
Amiy VermaNeuroanaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
Saurav SinghNeuroanaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
Surya K DubeNeuroanaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Ventilating acute brain injury patients, with normal lung, using low tidal volume (LTV) ventilation may lead to improved outcomes. Nonetheless, investigations are ongoing to understand its impact on intracranial pressure and cerebral oxygenation. Our study aimed to see the effect of LTV on optic nerve sheath diameter (ONSD) and regional cerebral oxygen saturation (rScO Material and Methods: This single-center, prospective, single-blinded, pre-post interventional study included 18 patients with sTBI who were mechanically ventilated with standard high tidal volume (HTV) ventilation (10 ml/kg). After recording outcome variables, ONSD and rScO Results: LTV had no effect on right ONSD ( Conclusions: Our findings suggest that LTV does not affect ONSD and rScO

Indexed as

Cerebral oxygenationlow tidal volume ventilationoptic nerve sheath diametersevere traumatic brain injury

Identifiers

PMID41542203
PMCPMC12803391

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.