Evidence map›Paper›PMID 41542080›Full record

ArticleComputational and structural biotechnology journal2025

STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures.

Jared K Slone, Minying Zhang, Peixin Jiang, Amanda Montoya, Emily Bontekoe, Barbara Nassif Rausseo, Alexandre Reuben, Lydia E Kavraki

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Technical review of artificial intelligence in TCR-T therapy.Journal of the National Cancer Center · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jared K SloneComputer Science, Rice University, Houston, 77005, TX, USA.
Minying ZhangThoracic/Head & Neck Medical Oncology, MD Anderson Cancer Center, Houston, 77030, TX, USA.
Peixin JiangThoracic/Head & Neck Medical Oncology, MD Anderson Cancer Center, Houston, 77030, TX, USA.
Amanda MontoyaThoracic/Head & Neck Medical Oncology, MD Anderson Cancer Center, Houston, 77030, TX, USA.
Emily BontekoeThoracic/Head & Neck Medical Oncology, MD Anderson Cancer Center, Houston, 77030, TX, USA.
Barbara Nassif RausseoThoracic/Head & Neck Medical Oncology, MD Anderson Cancer Center, Houston, 77030, TX, USA.
Alexandre ReubenThoracic/Head & Neck Medical Oncology, MD Anderson Cancer Center, Houston, 77030, TX, USA.
Lydia E KavrakiComputer Science, Rice University, Houston, 77005, TX, USA.

Funding

TRAINING PROGRAM IN COMPUTATIONAL BIOLOGY AND MEDICINET15LM007093 · NLM · RICE UNIVERSITY · PI Lydia E. Kavraki · 1992 to 2026
$20.8M
NLM NIH HHS T15 LM007093
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Geometric deep learningImmunologyProtein language modelProteomicsStructural bioinformaticsTCR, HLA

Identifiers

PMID41542080
PMCPMC12800378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.