Evidence map›Paper›PMID 41542018›Full record

ArticleEJHaem2026

Whole Genome and Single-Cell RNA Sequencing Reveals Clonal Evolution and Heterogeneity of Secondary Plasma Cell Leukemia: A Case Report.

Tomotaka Suzuki, Rui Yokomori, Takaomi Sanda, Masaki Ri, Shinsuke Iida

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJHaem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tomotaka SuzukiDepartment of Hematology and Oncology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Rui YokomoriCancer Science Institute of Singapore National University of Singapore Singapore.
Takaomi SandaDepartment of Hematology and Oncology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.ORCID https://orcid.org/0000-0003-1621-4954
Masaki RiDepartment of Hematology and Oncology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Shinsuke IidaDepartment of Hematology and Oncology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secondary plasma cell leukemia (sPCL) is a rare, aggressive manifestation of multiple myeloma (MM). We report a 75-year-old Japanese man with anemia as the chief complaint and IgG-λ MM that rapidly progressed to sPCL. Whole genome sequencing using Canopy revealed a major clone with a monoallelic

Indexed as

clonal evolutiongenomic instabilityplasma cell leukemiasingle‐cell RNA sequencingwhole genome sequencing

Identifiers

PMID41542018
PMCPMC12800386

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.