ArticleCureus2025
Association of Vitamin D Deficiency With Glycemic Control in Type 2 Diabetes Mellitus.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Background Insulin secretion and glucose metabolism are influenced by vitamin D. Deficiency can lead to a decrease in insulin sensitivity and a deterioration in glycemic control. Objectives This study's objective is to examine the association between serum vitamin D and glycemic control (HbA1c) among patients with type 2 diabetes mellitus (T2DM). Methods We studied 120 patients with T2DM. The measurement of vitamin D (25-hydroxyvitamin D (25(OH)D)) and HbA1c used established methods. Deficiency was classified as having a level of vitamin D < 20 ng/mL. Results Mean age was 52.6 ± 9.4 years; 70/120 (58.3%) were male. Vitamin D deficiency was present in 82/120 (68.3%). Mean HbA1c was higher in deficient vs sufficient patients (8.4 ± 1.2% vs 7.6 ± 1.0%, t = 3.82, p = 0.002). Fasting plasma glucose and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) were also higher in the deficient group (p ≤ 0.01). Serum vitamin D correlated negatively with HbA1c (r = -0.34, p = 0.001). Conclusion Vitamin D deficiency was common and associated with poorer glycemic control. Screening and treatment of deficiency may aid metabolic outcomes in T2DM.
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