Evidence map›Paper›PMID 41541906›Full record

ArticleIJU case reports2026

Administration of Desloratadine for Postorgasmic Illness Syndrome in a Japanese Teenager.

Kaoru Ito, Ko Kobayashi, Kohei Hashimoto, Wakako Yorozuya, Ko Okabe, Seisuke Nofuji, Yasuyuki Sakai, Yuki Kyoda, Toshiaki Tanaka, Noaya Masumori

Abstract read
In one paragraph

Article in IJU case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kaoru ItoDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Ko KobayashiDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Kohei HashimotoDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.ORCID https://orcid.org/0000-0003-0873-4642
Wakako YorozuyaDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Ko OkabeDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Seisuke NofujiDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Yasuyuki SakaiDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Yuki KyodaDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Toshiaki TanakaDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.
Noaya MasumoriDepartment of Urology Sapporo Medical University School of Medicine Sapporo Japan.ORCID https://orcid.org/0000-0001-6324-0739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Postorgasmic illness syndrome is a rare condition occurring after ejaculation. This syndrome can significantly affect the quality of life of patients. Case Presentation: A 17-year-old boy suffered from annoying fatigue, headache, photophobia and the sensation of a flu-like state. He did not know the trigger of these symptoms. He visited a psychiatry clinic where he was diagnosed with depression. Although he received administration of selective serotonin reuptake inhibitors, his symptoms continued. Then he noticed that his symptoms occurred after ejaculation by masturbation or wet dreams. He visited our outpatient clinic when he was 19 years old. We administered desloratadine. One month later the general malaise after ejaculation improved. Thereafter, all symptoms after ejaculation disappeared. Conclusions: A Japanese teenager suffering from postorgasmic illness syndrome was successfully treated with desloratadine. We believe that our experience will contribute to elucidating and treating this condition in the future.

Indexed as

antihistamineejaculatory disordermasturbationpostorgasmic illness syndromewet dreams

Identifiers

PMID41541906
PMCPMC12803729

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.