Evidence map›Paper›PMID 41541902›Full record

ArticleJPRAS open2026

The hidden mechanism of vacuum bell therapy: Local fat hypertrophy drives cosmetic outcome in adolescents with pectus excavatum.

Xiaoyan Feng, Peter Zimmermann, Martin Lacher, Oliver Johannes Deffaa, Nicole Burger, Johanna Pape, Franz Wolfgang Hirsch, Sebastian Krämer, Daniel Gräfe

Abstract read
In one paragraph

Article in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xiaoyan FengDepartment of Pediatric Surgery, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.
Peter ZimmermannDepartment of Pediatric Surgery, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.
Martin LacherDepartment of Pediatric Surgery, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.
Oliver Johannes DeffaaDepartment of Pediatric Surgery, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.
Nicole BurgerDepartment of Pediatric Surgery, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.
Johanna PapeDepartment of Pediatric Radiology, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.
Franz Wolfgang HirschDepartment of Pediatric Radiology, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.
Sebastian KrämerDivision of Thoracic Surgery, University Hospital, Liebigstraße 20, 04103 Leipzig, Germany.
Daniel GräfeDepartment of Pediatric Radiology, University Hospital, Liebigstraße 20a, 04103 Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Vacuum bell (VB) therapy is a non-invasive treatment option for pectus excavatum (PE), traditionally considered most effective in children under 12 due to greater skeletal remodeling potential. However, the extent and mechanisms of cosmetic improvement in older adolescents remain poorly understood. Methods: We retrospectively analyzed 19 male patients (median age 14.8 years) who underwent VB therapy for at least 1 year. Real-time MRI was performed before and after therapy to assess morphological changes. Key parameters included the Haller Index (HI), Correction Index (CI), and pectus excavation depth (PED). Additionally subcutaneous soft tissue thickness was measured at the deformity site and at the lateral thoracic wall. Results: After a median treatment duration of 1.8 years, HI and CI did not show significant reductions (HI: 5.4 to 5.3, Conclusions: The improvement in visual appearance of PE morphology during VB therapy results primarily from localized adipose tissue hypertrophy, while skeletal remodeling is likely to contribute to a much lesser degree. From a cosmetic perspective, these findings might justify the continued use of VB therapy beyond the traditional age threshold.

Indexed as

AdolescentsPectus excavatumReal-time magnetic resonance imagingVacuum bell

Identifiers

PMID41541902
PMCPMC12803859

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