Evidence map›Paper›PMID 41541825›Full record

ReviewJournal of Taibah University Medical Sciences2025

Effects of spirulina supplementation on growth parameters in malnourished children: A systematic review and meta-analysis.

Ima Sukmawati, Heri Ariyanto, Heni Heryani, Sri W Sundari, Miftahul Falah, Dika Rhousnaka, Yuyun Rahayu, Fitri Arofiati, Anna L Yusuf, Sri Susilawati and 1 more

Abstract readReview
In one paragraph

Review in Journal of Taibah University Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ima SukmawatiDepartment of Nursing, STIKes Muhammadiyah Ciamis, Indonesia.
Heri AriyantoDepartment of Nursing, STIKes Muhammadiyah Ciamis, Indonesia.
Heni HeryaniDepartment of Midwifery, STIKes Muhammadiyah Ciamis, Indonesia.
Sri W SundariDepartment of Midwifery, Universitas Muhammadiyah Tasikmalaya, Indonesia.
Miftahul FalahDepartment of Nursing, Universitas Muhammadiyah Tasikmalaya, Indonesia.
Dika RhousnakaDepartment of Nursing, STIKes Muhammadiyah Ciamis, Indonesia.
Yuyun RahayuDepartment of Nursing, STIKes Muhammadiyah Ciamis, Indonesia.
Fitri ArofiatiDepartment of Nursing, Universitas Muhammadiyah Yogyakarta, Indonesia.
Anna L YusufDepartment of Pharmacy, STIKes Muhammadiyah Ciamis, Indonesia.
Sri SusilawatiDepartment of Midwifery, Universitas Muhammadiyah Tasikmalaya, Indonesia.
Henri SetiawanDepartment of Nursing, STIKes Muhammadiyah Ciamis, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to investigate the effectiveness of spirulina supplementation in improving growth parameter outcomes among malnourished children. Methods: This study followed a systematic review and meta-analysis design. The inclusion criteria were experimental spirulina supplementation studies in children with chronic malnutrition, which were published in English between 2006 and 2025. Studies involving adult participants, and literature reviews, systematic reviews, and comprehensive reviews were excluded. A comprehensive search was conducted across five electronic databases: PubMed, Scopus, Wiley, ProQuest, and Emerald Insight. The quality of the included studies was assessed with the Joanna Briggs Institute Critical Appraisal Checklist. Data were quantitatively synthesized in Review Manager version 5.4. This review was prospectively registered in PROSPERO (CRD420251069286). Results: Seven studies in 1335 participants met the inclusion criteria. The meta-analysis indicated significant increases in weight (SMD = 0.33, 95 % CI [0.22, 0.45], Conclusion: Spirulina supplementation was found to have significant positive effects on weight and MUAC in children with chronic malnutrition, but no significant improvement in height. These findings support spirulina's potential role as a complementary intervention in nutritional programs targeting undernourished children.

Indexed as

ChildrenGrowthMalnutritionMicroalgaSpirulina

Identifiers

PMID41541825
PMCPMC12799548

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.