General practitioners' attitudes towards liquid biopsy as a diagnostic test for advanced lung cancer.

Danyon Lo, Jenny Wong, Rawiri Keenan, James Fingleton, Annie N M Wong

Abstract read

In one paragraph

Article in The journal of liquid biopsy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Danyon LoUniversity of Otago, Department of Medicine, PO Box 7343, Wellington, 6242, New Zealand.

Jenny WongUniversity of Waikato, Division of Health, Hillcrest Road, Hamilton, 3240, New Zealand.

Rawiri KeenanUniversity of Waikato, Division of Health, Hillcrest Road, Hamilton, 3240, New Zealand.

James FingletonUniversity of Otago, Department of Medicine, PO Box 7343, Wellington, 6242, New Zealand.

Annie N M WongUniversity of Otago, Department of Medicine, PO Box 7343, Wellington, 6242, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In New Zealand (NZ), lung cancer disproportionately affects our indigenous Māori population, with both incidence and mortality being three times higher than NZ Europeans. Incidence of endothelial growth factor receptor ( Methods: A survey was conducted of NZ GPs and was distributed through online channels between November 2023 to January 2024. Results: Seventy GPs responded and challenges reported with the diagnostic process of lung cancer were: limited GP appointments, poor access to imaging, and limited access to secondary care. 53/58 (91 %) of GPs were unaware of liquid biopsy. 46/58 (79 %) were initially not comfortable with pre-test genetic counselling associated for this. Some GPs highlighted the potential of liquid biopsy to complement existing procedures particularly in rural areas although concerns were expressed regarding culturally appropriate pathways. Provided adequate training and funding for liquid biopsy, 42/58 (72 %) of GPs stated they would be comfortable requesting liquid biopsy and the associated counselling. Conclusion: Most GPs were not familiar with liquid biopsy but 72 % supported these tests to be incorporated into current pathways. Liquid biopsy could potentially reduce diagnostic delays and inequities in lung cancer.

Indexed as

Circulating tumour DNAGeneral practiceLiquid biopsyLung cancerMolecular test

Identifiers

PMID41541744

DOI10.1016/j.jlb.2025.100330

PMCPMC12799498

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.