Evidence map›Paper›PMID 41541710›Full record

ArticleFood science & nutrition2026

Effect of Targeted Probiotics on Anesthesia-Induced Sleep Disturbances via Modulating the Gut Microbiome and Metabolites.

Rui-Zhi Yang, Song Lin, Le-Tong Huang, Jing Weng, Qiao-Ming Liu, Han-Shen Chen, Ning Ruan, Kai Zeng

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui-Zhi YangDepartment of Anesthesiology The First Affiliated Hospital of Fujian Medical University Fuzhou China.
Song LinDepartment of Anesthesiology The First Affiliated Hospital of Fujian Medical University Fuzhou China.
Le-Tong HuangDepartment of Anesthesiology The First Affiliated Hospital of Fujian Medical University Fuzhou China.
Jing WengDepartment of Anesthesiology The First Affiliated Hospital of Fujian Medical University Fuzhou China.
Qiao-Ming LiuDepartment of Anesthesiology The First Affiliated Hospital of Fujian Medical University Fuzhou China.
Han-Shen ChenDepartment of Anesthesiology The First Affiliated Hospital of Fujian Medical University Fuzhou China.
Ning RuanNational Regional Medical Center, Binhai Campus of the First Affiliated Hospital Fujian Medical University Fuzhou China.
Kai ZengDepartment of Anesthesiology The First Affiliated Hospital of Fujian Medical University Fuzhou China.ORCID https://orcid.org/0000-0002-4343-3207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-operative/post-anesthesia sleep disturbances are a major concern to patients, impacting recovery and overall well-being. Probiotics may offer potential benefits for sleep promotion by modulating microbial diversity and abundance. This study aimed to investigate the effect of targeted probiotic treatment on anesthesia-induced sleep disturbances and its impact on the microbiota and metabolites in the gut and lungs. Eight-week-old male SD rats received a continuous inhalation of isoflurane, combined with oral yogurt treatment without or containing probiotic

Indexed as

anesthesiagut microbiomelung microbiomemetabolitesprobioticssleep

Identifiers

PMID41541710
PMCPMC12802074

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.