Evidence map›Paper›PMID 41541685›Full record

ArticleiScience2026

Analyzed PD-L1-positive subpopulations by dual-labeling TSA-IF-FISH predicts immunotherapy efficacy in advanced lung cancer.

Lin Chen, Zhonglin Yang, Yue Lu, Shan Li, Dongjiang Tang, Lei Zhang

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lin ChenMOE International Joint Research Laboratory on Synthetic Biology and Medicines, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510640, P.R. China.
Zhonglin YangZhuhai Sanmed Biotech Ltd., 266 Tongchang Road, Zhuhai 519060, P.R. China.
Yue LuZhuhai Sanmed Biotech Ltd., 266 Tongchang Road, Zhuhai 519060, P.R. China.
Shan LiMOE International Joint Research Laboratory on Synthetic Biology and Medicines, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510640, P.R. China.
Dongjiang TangZhuhai Sanmed Biotech Ltd., 266 Tongchang Road, Zhuhai 519060, P.R. China.
Lei ZhangMOE International Joint Research Laboratory on Synthetic Biology and Medicines, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510640, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evaluation of predictive biomarkers in advanced lung cancer requires methods that can comprehensively profile rare cell populations. We developed a dual-labeling assay integrating tyramide signal amplification immunofluorescence (TSA-IF) with fluorescence

Indexed as

health sciences

Identifiers

PMID41541685
PMCPMC12799786

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.