Evidence map›Paper›PMID 41541649›Full record

ArticleGastro hep advances2026

Gas-forming Pyogenic Liver Abscess Mimicking Gastric Perforation in a Patient With Diabetic Ketoacidosis and Subsequent Rupture: A Case Report.

Tairyu Sato, Koki Yamada, Akira Nishio, Yuki Tokuda, Chihiro Yamanaka, Keishi Oka, Kanako Morita, Chihiro Tarumi, Kazuna Hazu, Yuki Nishiura and 10 more

Abstract readCase Reports
In one paragraph

Article in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Tairyu SatoDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Koki YamadaDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Akira NishioDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Yuki TokudaDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Chihiro YamanakaDepartment of Surgery, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Keishi OkaDepartment of Surgery, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Kanako MoritaDepartment of Diabetes and Endocrinology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Chihiro TarumiDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Kazuna HazuDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Yuki NishiuraDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Kumi HigashiharaDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Shogo NagahamaDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Takayuki MatsumaeDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Tadashi KegasawaDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Aya IshimiDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Satoshi HiyamaDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Katsumi YamamotoDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Nobuyuki TatsumiDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Osakuni MorimotoDepartment of Surgery, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.
Akira KanekoDepartment of Gastroenterology and Hepatology, Japan Community Healthcare Organization, Osaka Hospital, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 53-year-old man with uncontrolled diabetes presented with fever and diabetic ketoacidosis. Computed tomography revealed a large hepatic lesion containing mottled gas, but the origin was uncertain, delaying drainage and raising concern for gastric perforation. Next-morning computed tomography showed hepatic gas and free intraperitoneal air, yet abdominal findings were minimal. During percutaneous drainage planning, he developed sudden abdominal pain and septic shock, illustrating the rapid, life-threatening course of gas-forming pyogenic liver abscess. Urgent laparoscopy confirmed rupture; Klebsiella pneumoniae was isolated. This case highlights diagnostic challenges and need for prompt reassessment and source control. Uncontrolled diabetes and ketoacidosis likely accelerated gas-forming pyogenic liver abscess rupture.

Indexed as

Diabetic KetoacidosisEmphysematous Liver AbscessGas-Forming Pyogenic Liver AbscessGastric PerforationKlebsiella PneumoniaeLaparoscopyRuptureSource Control

Identifiers

PMID41541649
PMCPMC12800590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.