Evidence map›Paper›PMID 41541510›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2025

Opioid Use and Pain Decrease Between Days 3 and 7 After Quadriceps Tendon Anterior Cruciate Ligament Reconstruction in Adolescents.

Christopher J DeFrancesco, Morgan Swanson, Brendan A Williams, Vineet M Desai, Richa Gandhi, Divya Talwar, Theodore J Ganley

Abstract read
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Article in Arthroscopy, sports medicine, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Christopher J DeFrancescoDivision of Orthopedics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.
Morgan SwansonDivision of Orthopedics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.
Brendan A WilliamsDivision of Orthopedics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.
Vineet M DesaiHarvard Medical School, Boston, Massachusetts, U.S.A.
Richa GandhiMeharry Medical College, Nashville, Tennessee, U.S.A.
Divya TalwarDivision of Orthopedics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.
Theodore J GanleyDivision of Orthopedics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To detail pain levels and opioid consumption in the week following quadriceps tendon autograft (QT) anterior cruciate ligament (ACL) reconstruction among adolescents. Methods: Adolescents (<19 years) undergoing ACL reconstruction with QT using an all-inside technique were enrolled at the time of surgery. All underwent general anesthesia with femoral and sciatic nerve blocks. A subset had an indwelling femoral nerve catheter until postoperative day (POD) 2. Numeric Rating Scale pain level (scale 0-10) and opioid use at defined intervals (4 PM to 12 AM the evening of surgery, 12 AM to 8 AM on POD1, 8 AM to 4 PM on POD1, POD3, and POD7) were recorded via surveys. Patients who did not return at least half of their pain surveys were excluded, and all had a minimum of POD3 follow-up. Pain levels were summarized, and pairwise comparisons between the subgroups with and without femoral nerve catheters were done. Univariate tests were performed to evaluate the association between recorded variables and outcomes of POD3 opioid use or POD3 pain ≥5. Results: Fifty-eight patients were included. A median of 15 tablets of 5 mg of oxycodone were prescribed. On POD3, 26.8% of patients reported pain ≥5, and 26.8% reported opioid use. On POD7, 5.5% of patients reported pain ≥5, and 3.6% reported opioid use. In total, 35.2% never reported opioid use. Patients with indwelling femoral nerve catheters had lower opioid consumption during the 12 AM to 8 AM timeframe the night after surgery (0% vs 37.8%, Conclusions: In adolescents, moderate pain may persist for 3 days after ACL reconstruction with QT, even with regional blocks. However, both substantial pain and opioid use are uncommon at POD7. Level of Evidence: Level IV, retrospective therapeutic case series.

Identifiers

PMID41541510
PMCPMC12800834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.