Evidence map›Paper›PMID 41541496›Full record

ArticleRespirology case reports2026

Primary Malignant Melanoma of the Lung With a Long-Term Course: A Case Report.

Yusei Fukushima, Masanori Azuma, Yoshimi Miyagi, Mika Kitamura, Kodai Miyamoto, Yukari Mizuki, Soichiro Nakayama, Tetsuya Ueda

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yusei FukushimaDepartment of Respiratory Medicine Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.
Masanori AzumaDepartment of Respiratory Medicine Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.ORCID https://orcid.org/0009-0008-6049-9161
Yoshimi MiyagiDepartment of Diagnostic Pathology Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.
Mika KitamuraDepartment of Respiratory Medicine Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.
Kodai MiyamotoDepartment of Respiratory Medicine Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.
Yukari MizukiDepartment of Respiratory Medicine Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.
Soichiro NakayamaDepartment of Respiratory Medicine Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.
Tetsuya UedaDepartment of Respiratory Medicine Osaka Saiseikai Nakatsu Hospital Osaka City Osaka Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 66-year-old man with a 20-year history of recurrent haemoptysis presented with mild bronchiectasis and linear opacities detected on chest computed tomography (CT). The lesion was followed up annually and gradually enlarged into a mass over 10 years. Multiple bilateral pulmonary nodules were noted at 78 years of age. Surgical biopsy revealed malignant melanoma without evidence of other primary lesions on dermatological examination or positron emission tomography-CT. The patient was treated with nivolumab and achieved stable disease for 8 months before discontinuation owing to immune-related adverse events. Rapid disease progression was observed, and the patient died 14 months after initiating immunotherapy. Autopsy demonstrated extensive metastatic dissemination and marked tumour necrosis with CD8+ T-cell infiltration in the lung tumour, indicating a therapeutic response to nivolumab. These findings highlight the potential association between chronic airway inflammation and tumour development and suggest that immunotherapy could play a role in treating PMML.

Indexed as

bronchiectasiscase reporthaemoptysisimmunochemotherapyprimary malignant melanoma of the lung

Identifiers

PMID41541496
PMCPMC12803749

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.