Evidence map›Paper›PMID 41541207›Full record

ArticleRSC advances2026

Design, synthesis, and biological evaluation of novel chalcone derivatives: integrating molecular docking with

Abida Shamim, Humaira Nadeem, Syed Muzzammil Masaud, Tajamul Hussain, Kashif Bashir, Salman Alrokayan, Ihsan-Ul Haq, Muhamamd Latif, Muhammad Imran, Nadeem Irshad

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abida ShamimDepartment of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad 45320 Pakistan abidashamim@bs.qau.edu.pk kbashir@qau.edu.pk ihaq@qau.edu.pk nirshad@qau.edu.pk +925190644099.
Humaira NadeemRiphah Institute of Pharmaceutical Sciences, Riphah International University Islamabad Pakistan humaira.nadeem@riphah.edu.pk muzzammil.masaud@riphah.edu.pk.
Syed Muzzammil MasaudRiphah Institute of Pharmaceutical Sciences, Riphah International University Islamabad Pakistan humaira.nadeem@riphah.edu.pk muzzammil.masaud@riphah.edu.pk.
Tajamul HussainCenter of Excellence in Biotechnology Research, King Saud University Riyadh 11451 Saudi Arabia thussain@ksu.edu.sa.ORCID https://orcid.org/0000-0001-7601-1417
Kashif BashirDepartment of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad 45320 Pakistan abidashamim@bs.qau.edu.pk kbashir@qau.edu.pk ihaq@qau.edu.pk nirshad@qau.edu.pk +925190644099.
Salman AlrokayanResearch Chair for Biomedical Application of Nanomaterials, Biochemistry Department, College Fof Science, King Saud University Riyadh 11451 Saudi Arabia salrokayan@ksu.edu.sa.
Ihsan-Ul HaqDepartment of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad 45320 Pakistan abidashamim@bs.qau.edu.pk kbashir@qau.edu.pk ihaq@qau.edu.pk nirshad@qau.edu.pk +925190644099.
Muhamamd LatifCentre for Genetics and Inherited Diseases (CGID), Taibah University Madinah 42353 Saudi Arabia latifmayo@gmail.com.ORCID https://orcid.org/0000-0003-4858-3324
Muhammad ImranState Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University Shanghai P. R. China imran93@sjtu.edu.cn.
Nadeem IrshadDepartment of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad 45320 Pakistan abidashamim@bs.qau.edu.pk kbashir@qau.edu.pk ihaq@qau.edu.pk nirshad@qau.edu.pk +925190644099.ORCID https://orcid.org/0009-0000-0638-2271

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic inflammatory disorders are often accompanied by persistent pain, yet current therapies remain limited by modest efficacy and adverse effects. To address this challenge, a series of eleven chalcone-based derivatives was synthesized

Identifiers

PMID41541207
PMCPMC12801139

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.