Evidence map›Paper›PMID 41541166›Full record

ArticleInternational journal of surgery case reports2025

Benign but bizarre: A case report on idiopathic scrotal calcinosis.

Amol Gupta, Sanjeev Gianchandani, Swati Deshpande, Vasundhara Gopalan, Jhanwi Khurana, Arushi Kaul

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amol GuptaDatta Meghe Institute of Higher Education and Research Deemed to be University, General Surgery, Wardha, 442001, Maharashtra, India.
Sanjeev GianchandaniDatta Meghe Institute of Higher Education and Research Deemed to be University, General Surgery, Wardha, 442001, Maharashtra, India.
Swati DeshpandeDatta Meghe Institute of Higher Education and Research Deemed to be University, General Surgery, Wardha, 442001, Maharashtra, India.
Vasundhara GopalanDatta Meghe Institute of Higher Education and Research Deemed to be University, General Surgery, Wardha, 442001, Maharashtra, India.
Jhanwi KhuranaDatta Meghe Institute of Higher Education and Research Deemed to be University, General Surgery, Wardha, 442001, Maharashtra, India.
Arushi KaulDatta Meghe Institute of Higher Education and Research Deemed to be University, General Surgery, Wardha, 442001, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: Calcinosis cutis, also known as calcification in soft tissue, is an uncommon benign condition that can be further classified into idiopathic, dystrophic, iatrogenic, metastatic, and calciphylaxis subtypes. The scrotum is one area where calcinosis cutis frequently occurs. During years or decades, the nodules gradually enlarge. The scrotal calcinosis cutis can be solitary or multiple, typically asymptomatic, hard, yellowish marble-like, polypoidal. Despite being benign, patients with this condition present late due to shyness or cancer anxiety, even when faced with sexual discomfort and infertility. In this article, we want to raise awareness to highlight benignity of this condition, various treatment options and good prognosis associated with the disease. Case presentation: A 38-year-old male presented with multiple painful, itchy scrotal swellings and infertility. Examination revealed scrotal nodules, absent left testis, and aspermia. Histopathology confirmed scrotal calcinosis. Total scrotectomy was performed with right testis repositioned in the thigh. Patient was referred for infertility management after successful surgical recovery. Clinical discussion: Idiopathic calcinosis cutis of the scrotum (ICCS) is a benign, slow-growing condition often presenting in adulthood with asymptomatic yellowish nodules. Diagnosis is confirmed histologically. Though idiopathic, it may involve dystrophic calcification of epidermoid cysts. Surgical excision with scrotal reconstruction is the preferred treatment, offering excellent cosmetic and curative outcomes. Conclusion: Being usually asymptomatic, ICCS is a benign disorder. It appears as a series of successive, different-sized nodules. A histological evaluation shows the calcified regions. One of two possible causes exists: idiopathic or dystrophic calcification of cysts. Excision is the preferred course of action.

Indexed as

Calcinosis cutisDystrophicIdiopathicScrotum

Identifiers

PMID41541166
PMCPMC12648506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.