Evidence map›Paper›PMID 41541158›Full record

ArticleInternational journal of surgery case reports2025

Redo aortic valve replacement in twin pregnancy: navigating high-risk cardiac surgery with maternal and fetal success - A case report.

Syed Shamair Ali Rizvi, Muhammad Nabeel Safdar, Sara Iqbal, Farhala Baloch, Shazia Masheer, Syed Shahabuddin

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In one paragraph

Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Syed Shamair Ali RizviMedical College, Aga Khan University, Karachi, Pakistan.
Muhammad Nabeel SafdarSection of Cardiothoracic Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.
Sara IqbalSection of Cardiothoracic Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.
Farhala BalochDepartment of Medicine (Cardiology), Aga Khan University Karachi, Pakistan.
Shazia MasheerDepartment of Maternal and Child Health, Aga Khan University Hospital, Karachi, Pakistan.
Syed ShahabuddinSection of Cardiothoracic Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: Redo aortic valve replacement (AVR) in pregnancy presents significant challenges due to maternal hemodynamics, fetal well-being, and anticoagulation management. Prosthetic valve stenosis is a life-threatening condition and can significantly alter the maternal and fetal outcome without treatment. We report a case of a pregnant woman with twin gestation who developed prosthetic valve stenosis due to pannus formation and requiring redo AVR. Case presentation: A 31-year-old woman, pregnant with dichorionic diamniotic twins at 14 weeks, presented with worsening dyspnea. She had undergone mechanical AVR at 11 years of age and was on warfarin; however, she stopped taking warfarin since 2014. Echocardiography revealed prosthetic aortic valve stenosis, with severely elevated transvalvular gradients. She underwent redo AVR with a 21 mm On-X mechanical valve following aortic root enlargement. Postoperatively, she developed complete atrioventricular dissociation, requiring a permanent pacemaker. Multidisciplinary care ensured fetal viability, and she was discharged in stable condition with appropriate anticoagulation management. Discussion: Redo AVR during pregnancy requires meticulous planning, balancing maternal and fetal risks. This case highlights the complexities of anticoagulation strategies, surgical execution, and maternal-fetal monitoring. Conclusion: A multidisciplinary approach is essential to optimize outcomes in pregnant patients undergoing redo AVR. Long-term follow-up is crucial for continued surveillance of prosthetic valve function and maternal health.

Indexed as

Aortic valve replacementCardiac surgeryCase reportPatient-prosthesis mismatchPregnancyProsthetic valve thrombosis

Identifiers

PMID41541158
PMCPMC12639255

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