Evidence map›Paper›PMID 41541069›Full record

ReviewInfectious medicine2025

Potential mechanisms linking bacterial factors to the development and progression of multiple sclerosis.

Aysouda Jafari-Nakhjavanlou, Parsa Irajian, Abed Zahedi Bialvaei

Abstract readReview
In one paragraph

Review in Infectious medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aysouda Jafari-NakhjavanlouMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran 1449614535, Iran.
Parsa IrajianMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran 1449614535, Iran.
Abed Zahedi BialvaeiMicrobial Biotechnology Research Center, Iran University of Medical Sciences, Tehran 1449614535, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is a chronic neurodegenerative and autoimmune disease of the central nervous system (CNS). While the exact etiology remains unclear, emerging evidence suggests that bacterial toxins play significant roles in MS pathogenesis and progression. We aimed to review mechanisms by which bacterial toxins influence MS development, focusing on molecular mimicry, epitope spreading, bystander activation, and blood-brain barrier (BBB) disruption. Specific toxins, including

Indexed as

AutoimmuneBacterial toxinCentral nervous systemMicrobiomeMultiple sclerosis

Identifiers

PMID41541069
PMCPMC12800763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.