Evidence map›Paper›PMID 41541001›Full record

Trial reportJournal of diabetes research2026

The Effect of Atmospheric Saturated Oxygen Combined With Intelligent Upper and Lower Limb Rehabilitation Training on Diabetic Lower Extremity Arterial Disease.

Zi-Bo Liu, Li-Chun Wang, Yang Li, Long Zhao, Qiu-Xiao Zhu, Hong-Li Zhang, Hong-Ling Li

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of diabetes research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zi-Bo LiuDepartment of Endocrinology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China, hebmu.edu.cn.
Li-Chun WangRehabilitation Department, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, Hebei, China.
Yang LiThe Second Department of Rehabilitation, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China, hebmu.edu.cn.
Long ZhaoThe Second Department of Rehabilitation, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China, hebmu.edu.cn.
Qiu-Xiao ZhuDepartment of Endocrinology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China, hebmu.edu.cn.
Hong-Li ZhangRehabilitation Department, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, Hebei, China.
Hong-Ling LiThe Second Department of Rehabilitation, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China, hebmu.edu.cn.ORCID https://orcid.org/0000-0002-5336-8701

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study is to explore the effect of bedside normobaric saturated oxygen inhalation combined with upper and lower limb rehabilitation training on diabetic lower extremity arterial disease (LEAD). Methods: From January 2022 to December 2023, 60 DM-LEAD patients from the Second Hospital of Hebei Medical University were randomly divided into control (30 cases) and study (30 cases) groups. Both received standard treatment; the control group added MOTOmed-based limb rehabilitation training, and the study group further received atmospheric saturated oxygen therapy. Pre- and posttreatment indices (VAS, Barthel index, blood glucose, blood lipid, inflammatory factors, ABI, TcPO Results: Both groups improved posttreatment (all Conclusion: The combined therapy improves pain and daily living abilities, delays DM-LEAD progression, may reduce amputation risk, and improves outcomes. Long-term effects need further study.

Indexed as

Diabetic AngiopathiesExercise TherapyLower ExtremityOxygenOxygen Inhalation TherapyPeripheral Arterial DiseaseUpper ExtremityAgedFemaleHumansMaleMiddle AgedTreatment OutcomeOxygenatmospheric saturated oxygendiabetic lower extremity arterial diseaseexercise therapy

Identifiers

PMID41541001
PMCPMC12800565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.