Evidence map›Paper›PMID 41540925›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2026

Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026.

Allan De Clercq, François Blanquart, Vincent Vieillefond, Benoit Visseaux, Alexandra Jacques, Stéphanie Haim-Boukobza, Valentin Wehrle, Guillaume Deleglise, Thomas Duret, Sibylle Bernard-Stoecklin and 8 more

Erratum issuedAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Cross-sectional study on protective antibodies against influenza A virus subtypes and cross-protection against influenza A(H3N2) subclade K, Portugal, August 2025.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  6. Modest protection from vaccination against influenza A(H3N2) subclade K, Beijing, China, 2025/26 season.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Allan De ClercqHospices Civils de Lyon (HCL), Centre National de Référence des virus des infections respiratoires, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.
François BlanquartCenter for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, PSL Research University, Paris, France.
Vincent VieillefondBIOGROUP Paris Ouest, Levallois Perret, France.
Benoit VisseauxDépartement d'infectiologie, Laboratoire Cerba, Cerba Healthcare, Frépillon, France.
Alexandra JacquesBiogroup Lorraine, Grand Est, Metz, France.
Stéphanie Haim-BoukobzaLaboratoires Cerballiance, Cerba Healthcare, Issy-les-Moulineaux, France.
Valentin WehrleBioLBS, Lillebonne, France.
Guillaume DelegliseINOVIE GEN-BIO, Clermont-Ferrand, France.
Thomas DuretINOVIE GEN-BIO, Clermont-Ferrand, France.
Sibylle Bernard-StoecklinSanté Publique France - Direction des maladies infectieuses, Saint-Maurice, France.
Danielle Perez-BercoffNational Reference Center for Respiratory Viruses, Molecular Mechanisms of Multiplication of Pneumovirus, Institut Pasteur, Université Paris Cité, Paris, France.
Antoine ObletteHospices Civils de Lyon (HCL), Centre National de Référence des virus des infections respiratoires, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.
Bruno LinaHospices Civils de Lyon (HCL), Centre National de Référence des virus des infections respiratoires, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.
Marie Anne Rameix-WeltiNational Reference Center for Respiratory Viruses, Molecular Mechanisms of Multiplication of Pneumovirus, Institut Pasteur, Université Paris Cité, Paris, France.
Laurence JossetHospices Civils de Lyon (HCL), Centre National de Référence des virus des infections respiratoires, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.
Vincent EnoufNational Reference Center for Respiratory Viruses, Molecular Mechanisms of Multiplication of Pneumovirus, Institut Pasteur, Université Paris Cité, Paris, France.
Antonin BalHospices Civils de Lyon (HCL), Centre National de Référence des virus des infections respiratoires, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.
RELAB study groupThe members of the RELAB study group are listed under Acknowledgements.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Europe, the 2025/26 seasonal influenza epidemic started in October 2025. Co-circulation of A(H3N2) and A(H1N1)pdm09 was observed in several countries including France. We estimated early vaccine effectiveness (VE) against influenza virus in French outpatients (5,451 positives/18,816 negatives). A significant VE across all age groups was measured: 28% (95% CI: 17-37) for those aged ≥ 65 years, 45% (95% CI: 36-53) for 18-64-year-olds and 57% (95% CIs: 29-74) for 0-17-year-olds. Reinforcing vaccination uptake is warranted.

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanInfluenza VaccinesOutpatientsVaccinationVaccine EfficacyAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleFranceHumansInfluenza Vaccinesacute respiratory infectionInfluenzasurveillancevaccine effectiveness

Identifiers

PMID41540925
PMCPMC12811705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.