ArticleBrain and behavior2026
Case-Controlled Clinical Assessment of the Olfactory System via Cranial Magnetic Resonance Imaging in Patients With Type 2 Diabetes Mellitus.
Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Case-Controlled Clinical Assessment of the Olfactory System via Cranial Magnetic Resonance Imaging in Patients With Type 2 Diabetes Mellitus.Brain and behavior · 2026Article
- Olfactory Performance of Children and Adolescents With Type 1 Diabetes: Relationship to Diabetes Duration and Glycemic Control.Journal of diabetes research · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study is to assess the olfactory system of patients with T2DM using the cranial magnetic resonance imaging (MRI) method.
methodThis is a retrospective case-control study in which a group of T2DM patients and a control group were compared. The results of the examinations of the olfactory systems of the patients by cranial MRI were transferred to a data collection form. Descriptive statistical methods, chi-squared tests, the Mann-Whitney U test, and Spearman's correlation coefficient were used to analyze the data.
resultsIt was determined that 66.7% of the case group were women, the mean age of the patients in the group was 52.50 ± 7.41, and their mean T2DM diagnosis duration was 6.48 ± 3.18 years. There were statistically significant differences between the case and control groups in terms of their olfactory bulb volume (OBV), olfactory tract length (OTL), and olfactory sulcus depth (OS) values. Longer T2DM durations and elevated HbA1c levels were significantly associated with structural disorders of the olfactory system (p < 0.01).
conclusionA longer duration of T2DM and elevated HbA1c levels trigger the structural disorders of the olfactory system. In comparison to healthy controls, we identified prominent changes in the olfactory bulb volumes, olfactory tract lengths, and olfactory sulcus depths of T2DM patients. This reveals the need for T2DM patients to pay more attention to their diet and insulin treatment. Similarly, olfactory dysfunction in T2DM patients should be carefully monitored by clinicians.
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