Evidence map›Paper›PMID 41540482›Full record

ReviewJournal of translational medicine2026

Functional regulation of GlycoRNA and progress in malignant tumors.

Ziyan Liu, Xiaoyan Wang, Changfeng Man, Shiqi Zhang, Dandan Gong, Yakun Lang, Yu Fan

Abstract readReview
In one paragraph

Review in Journal of translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ziyan Liu *Cancer Institue, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China.
Xiaoyan Wang *Digestive Department, The Suqian Clinical College of Xuzhou Medical University, Jiangsu, Suqian, People's Republic of China.
Changfeng Man *Cancer Institue, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China.
Shiqi ZhangDigestive Department, The Suqian Clinical College of Xuzhou Medical University, Jiangsu, Suqian, People's Republic of China.
Dandan GongCancer Institue, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China. godan121986@163.com.
Yakun LangCancer Institue, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China. lyk11223@sina.com.
Yu FanCancer Institue, The Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China. yuf12345@ujs.edu.cn.ORCID 0000-0003-4288-2999

Funding

Key project fund of Jiangsu Provincial Health Commission ZD2022052, K2023016Suqian science and technology support project fund KY202203Zhenjiang Key Research and Development Fund SH2024002, SH2024075, JC0004031Zhenjiang Key Research and Development Fund SH2024002, SH2024075, JC2024031
6 · The paper itself

Abstract

backgroundGlycans form unique GlycoRNAs through covalent modification of RNA molecules. GlycoRNAs serve as key components in intercellular communication. Early diagnosis and treatment of malignant tumors have always been the focus of cancer research, and the emergence of GlycoRNA has brought new opportunities to this field. MAIN BODY: With breakthroughs in detection technologies, the structure and function of GlycoRNA are being gradually revealed. Here we describe the multiple biological functions of GlycoRNA and discuss the newly discovered GlycoRNA present in the exosomal lumen. This article primarily focuses on the structure and functional regulation of GlycoRNA, as well as detection technologies, to illustrate its potential in tumor diagnosis and treatment.

conclusionOur aim is to provide new perspectives for GlycoRNA biology research and promote its applications in malignant tumors.

Indexed as

Disease ProgressionNeoplasmsAnimalsHumans

Identifiers

PMID41540482
PMCPMC12930660

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.