ArticleEuropean journal of medical research2026
Stress hyperglycemia ratio predicts outcome in stroke patients without diabetes and builds a nomogram: a multi-center retrospective cohort study in a Chinese population.
Article in European journal of medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo explore how diabetes influences the association between stress hyperglycemia (SH) and functional outcomes in acute ischemic stroke (AIS), and to develop a nomogram based on the stress hyperglycemia ratio (SHR) to predict the prognosis of AIS patients.
methodsPatients were divided into diabetic mellitus (DM) and non-diabetic mellitus (non-DM) groups. SH was calculated using the ratio of fasting blood sugar (FBG) to glycosylated hemoglobin A1c (HbA1c). Poor functional outcomes were defined as a modified Rankin Scale (mRS) score > 2 at a 3-month follow-up. Multivariable logistic regression analysis was used to identify the relationship between SHR and functional outcomes in diabetic and non-diabetic groups. Least Absolute Shrinkage Selection Operator (LASSO) regression analysis and logistic regression analysis were employed to build a nomogram.
resultsIn the DM group, severe stress hyperglycemia showed no significant association with poor function outcomes at 3 months. However, in the non-DM group, severe stress hyperglycemia was associated with poor function outcomes [odds ratio (OR) = 2.21, 95% confidence interval CI 1.61-3.02, p < 0.001]. After adjusting for covariates, the differences remained statistically significant (adjusted OR = 1.62, 95% CI 1.09-2.42, p = 0.0181). Lasso regression identified 8 predictive factors, while logistic regression highlighted age, NIHSS, and SHR as independent predictors, forming a nomogram. The receiver operating characteristic curve assessed the discriminative ability of the nomogram, calibration, and clinical decision curves to evaluate model fitting and net benefit.
conclusionSevere stress hyperglycemia is linked to worse outcomes in non-diabetic patients but not significantly correlated in diabetic patients. A nomogram incorporating age, SHR, and NIHSS predicts poor outcomes in non-diabetic patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.