Evidence map›Paper›PMID 41540393›Full record

ArticleBMC musculoskeletal disorders2026

Clinical and cadaveric evidence for inlay technique fixation in ruptured MCL inferior attachment treatment.

Yu Zhang, Wentian Gao, Qiangqiang Li, Aikeremu Aierken, Ping Dong, Yukun Zhou, Jianan Ding, Peng Sun, Yuejian Ding, Qing Jiang and 1 more

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu ZhangDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, Jiangsu, PR China.
Wentian GaoDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Drum Tower Hospital Affiliated of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, Jiangsu, PR China.
Qiangqiang LiDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, Jiangsu, PR China.
Aikeremu AierkenDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Drum Tower Hospital Affiliated of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, Jiangsu, PR China.
Ping DongNanjing University Medical School, Nanjing, Jiangsu, PR China.
Yukun ZhouNanjing University Medical School, Nanjing, Jiangsu, PR China.
Jianan DingDepartment of Orthopedic Surgery, Nanjing Central Hospital, Nanjing, Jiangsu, PR China.
Peng SunDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, Jiangsu, PR China.
Yuejian DingDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Drum Tower Hospital Affiliated of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, Jiangsu, PR China.
Qing JiangDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, Jiangsu, PR China. qingj@nju.edu.cn.
Dongyang ChenDivision of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, Jiangsu, PR China. 28617621@qq.com.

Funding

fundings for Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University 2022-LCYJ-MS-21fundings for Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University 2024-LCYJ-PY-82Nanjing Municipal Health Science and Technology Development Project YKK24103
6 · The paper itself

Abstract

backgroundAlthough well-documented for ligament graft fixation, the inlay technique remains largely unexplored for distal MCL avulsions, presenting a significant opportunity. A comprehensive evaluation of this approach utilizing an interference screw is now demanded, focusing on its biomechanical properties, kinematic influence, and ultimate clinical efficacy.

methodsThe MCL dynamic trajectories were recorded during full range of motion in three cadaveric specimens, and the mechanical strength were compared between inlay and onlay techniques using isokinetic tensile tests. Twenty-six patients with ruptured MCL inferior attachments underwent inlay technique fixation surgery 2 cm proximal to the distal insertion. Lateral stress tests, knee joint Lysholm scores, and MRIs used to evaluate knee stability and function.

resultsMCL dynamic trajectories showed no displacement within 3 cm of the ligament’s distal end during full range of motion. Inlay technique exhibited significantly higher mechanical strength and shorter displacement compared to onlay technique. Twenty-six patients underwent this surgical technique, with negative lateral stress and drawer tests post-operation. Knee joint Lysholm scores significantly increased from 30 (17,48) pre-operation to 65 (30,90) at 3 months, 81 (60,95) at 6 months, and 90 (83,95) at 12 months post-operation (P < 0.05). MRI results showed satisfactory tendon-bone healing and ligament tension.

conclusionsInlay technique offers superior mechanical strength, earlier stability and tendon-bone healing for treating the inferior attachment of the MCL. An upward shift of the MCL insertion point within 3 cm does not impair knee joint motion trajectory.

Indexed as

Medial Collateral Ligament, KneeAdultBiomechanical PhenomenaBone ScrewsCadaverFemaleHumansKnee JointMaleMiddle AgedRange of Motion, ArticularRuptureTreatment OutcomeYoung AdultBiomechanicsBone tunnel fixationInlay techniqueMedial collateral ligamentMotion trajectory

Identifiers

PMID41540393
PMCPMC12895789

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.