Evidence map›Paper›PMID 41540381›Full record

ReviewBMC medical education2026

Role of basic chemistry education in clinical pharmacy requirements: evidence from cross-sectional study and narrative review.

Yingshi Zhang, Ziang Xu, Zeming Tang, Yikun Zhang, Xiangbo Xu, Fangyuan Zheng, Xiaohong Sun, Mingyi Zhao

Abstract readReview
In one paragraph

Review in BMC medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingshi ZhangDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, No.103 of Wenhua Road, Liaoning, 110016, China.
Ziang XuDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, No.103 of Wenhua Road, Liaoning, 110016, China.
Zeming TangDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, No.103 of Wenhua Road, Liaoning, 110016, China.
Yikun ZhangDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, No.103 of Wenhua Road, Liaoning, 110016, China.
Xiangbo XuDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, No.103 of Wenhua Road, Liaoning, 110016, China.
Fangyuan ZhengDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, No.103 of Wenhua Road, Liaoning, 110016, China.
Xiaohong SunMedicine and Medical Equipment Supply Station of No.32653 Troops of PLA, Shenyang, 110026, China. dj200082@163.com.
Mingyi ZhaoDepartment of Clinical Pharmacy, Shenyang Pharmaceutical University, No.103 of Wenhua Road, Liaoning, 110016, China. zmy_dl@126.com.

Funding

Liaoning province education Science"14th Five year plan"2021 Annual Project JG21DA018National Training Program of Innovation and Entrepreneurship for Undergraduates 202410163039Natural Science Foundation of Liaoning Province 2025-MSLH-653Scientific Research Fund of Liaoning Provincial Education Department LJ212510163014
6 · The paper itself

Abstract

backgroundBasic chemistry knowledge is important for the work requirements of clinical pharmacists. However, it is not clear which types of basic chemistry teaching are the most important. The purpose of this study was to determine the most important types of chemistry education for the professional requirements of clinical pharmacists.

methodsSection I, a cross-sectional study was conducted through a questionnaire survey administered from December 2024 to February 2025 to collect data on the importance of analytical chemistry, inorganic chemistry, organic chemistry, medicinal chemistry, experimental medicinal chemistry, physical chemistry and biochemistry among undergraduate and graduate students who had received clinical pharmacist training, current clinical pharmacists or other personnel. Second II, we conducted a narrative review up through March 2025 that included our cross-sectional study and other publications to highlight the importance of various chemical education methods.

resultsIn Section I, a total of 600 participants were included in the cross-sectional study of the questionnaire survey. We found that all categories of participants believed that there was no disconnect between chemistry education and clinical rotation and that knowledge of medicinal chemistry and biochemistry were considered more important among participants with different levels and backgrounds. In addition, in terms of the application of chemical knowledge, we found that undergraduate and graduate students tended to infer the solubility and adverse reactions of medications through the chemical structural formulas in the instructions. In Section II, the narrative review revealed that medicinal chemistry and biochemistry play particularly important roles in meeting the demands of clinical pharmacists.

conclusionThrough cross-sectional research and narrative review, this study revealed that medicinal chemistry and biochemistry education are more important for the professional requirements of clinical pharmacists, especially for junior clinical pharmacists.

Indexed as

Chemistry, PharmaceuticalEducation, PharmacyCross-Sectional StudiesCurriculumFemaleHumansMaleSurveys and QuestionnairesBiochemistryChemistry educationClinical pharmacyCross-sectional studyMedicinal chemistry

Identifiers

PMID41540381
PMCPMC12892565

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.