ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2026
Deciphering the multifarious biomedicinal properties of marine-derived Streptomyces kunmingensis through In vitro, In silico and GC-MS-based metabolomic approaches.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Bacterial resistance, oxidative stress, inflammation, and cancer pose significant global health concerns. Current treatment protocols prove inadequate owing to adverse reactions and the emergence of resistant strains. In this context, this study explores the biomedicinal properties of an underexplored marine actinobacterium Streptomyces kunmingensis. Antibacterial activity inferred that the ethyl acetate extract of S. kunmingensis strenuously inhibited the growth of bacterial pathogens and violacein production by Chromobacterium violaceum. The extract effectively neutralized DPPH radicals (18.7%-85.5%) and affirmed its strong antioxidant properties. Anti-inflammatory activity (19.4%-80.6%) showed dose-dependent inhibition of hemolysis in red blood cells, and anti-arthritis activity (14.2%-74.5%) was confirmed by protein denaturation assay. Anticancer potential against A549 recorded an IC
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