Evidence map›Paper›PMID 41540240›Full record

ArticleCommunications medicine2026

The Reproductive Mental health of Ontario Virtual Intervention Network (MOVIN): a pilot randomized controlled trial.

S N Vigod, A Dalfen, C L Dennis, M Amato, S Grigoriadis, T Jamieson, K Bishop, S Lubotzky-Gete, M Michalowska, V Shah and 1 more

Abstract read
In one paragraph

Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

S N VigodDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada. simone.vigod@wchospital.ca.ORCID http://orcid.org/0000-0002-2736-9639
A DalfenDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.
C L DennisDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.
M AmatoDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.
S GrigoriadisDepartment of Psychiatry, Temerty Faculty of Medicine, University of Toronto (UofT), Toronto, ON, Canada.
T JamiesonDepartment of Medicine, Temerty Faculty of Medicine, UofT, Toronto, ON, Canada.
K BishopDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.
S Lubotzky-GeteDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.
M MichalowskaDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.
V ShahDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-5928-9369
N IversDepartment of Psychiatry, Women's College Hospital and Women's College Research and Innovation Institute, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-2500-2435

Funding

Women's College Hospital N/A
6 · The paper itself

Abstract

backgroundThe Reproductive Mental health of Ontario Virtual Intervention Network (MOVIN) aims to improve perinatal depression care across a large Canadian health jurisdiction. It involves a web-based platform, care coordinator for personalized treatment planning, and psychiatrist to liaise with primary care clinicians, and provide direct consultation as needed. This was a pilot randomized controlled trial (RCT) of MOVIN.

methodsParticipants aged ≥18 years, pregnant or within 12 months postpartum and with Edinburgh Postnatal Depression Scale (EPDS) score >12 recruited from across Ontario, Canada, were randomized 1:1 to MOVIN for 24 weeks or a control condition. The primary outcome was feasibility, inclusive of recruitment, acceptability, and research protocol follow-up. Depression symptom remission was a main secondary outcome for the pilot trial. EPDS scores and remission (EPDS ≤ 12) were compared between groups.

resultsOf 101 participants (n = 48 MOVIN; n = 53 control), 80% completed 24-week follow-up. Participant views of MOVIN were very positive (high acceptability) and multiple opportunities for protocol adjustment in a larger future study were identified. At 24 weeks post-randomization, EPDS scores were lower in MOVIN vs. controls, with a mean difference adjusted for baseline score of -2.32 (95% Confidence Interval, CI -4.23 to -0.42). At the same time point, 75.0% of the MOVIN group vs. 51.1% of controls were in remission (chi-square=4.83, p = 0.03).

conclusionsWith high feasibility, including in recruitment, acceptability, and research protocol adherence, and preliminary suggestion of efficacy, the results of this study support proceeding to a large-scale RCT of MOVIN to definitively evaluate its efficacy at a larger scale.

Identifiers

PMID41540240
PMCPMC12901973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.