Evidence map›Paper›PMID 41540055›Full record

ArticleBDJ open2026

The effect of Chlorohexidine, Er:YAG laser and diode laser 980 nm as dental cavity disinfectants on dentine morphology and microleakage of composite restoration: an in vitro study.

Mennatallah Khafagi, Mostafa Gheith, Haythem S Moharrum, Mohamed Abo Elyazeed Ahmed, Riham M Aly, Maryam El Mansy

Abstract read
In one paragraph

Article in BDJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mennatallah KhafagiResearch Assistant - Pediatric Dentistry Orthodontics and Pediatric Dentistry Department, Oral and Dental Research Institute, National Research Centre, Dokki, Giza Governorate, Egypt. ma.khafagy@nrc.sci.eg.ORCID http://orcid.org/0009-0008-2105-8101
Mostafa GheithProfessor of Laser applications in dental medicine, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt.
Haythem S MoharrumAssistant professor Department of Medical Applications of Laser, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt.
Mohamed Abo Elyazeed AhmedProfessor of Pediatric Dentistry Orthodontics and Pediatric Dentistry Department, Oral and Dental Research Institute, National Research Centre, Dokki, Giza Governorate, Egypt.
Riham M AlyStem Cell Laboratory, Center of Excellence for Advanced Sciences, National Research Centre, Cairo, Egypt, Department of Basic Dental Science, Oral Medicine & Dentistry Research Institute, National Research Centre, Dokki, Cairo, Egypt.
Maryam El MansyResearcher of Pediatric Dentistry, Orthodontics and Pediatric Dentistry Department, Oral and Dental Research Institute, National Research Centre, Dokki, Giza Governorate, 12622, Egypt.ORCID http://orcid.org/0000-0002-5395-1710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionResidual microorganisms may remain even after thorough mechanical cavity preparation, leading to secondary caries. Additionally, the smear layer generated during this process can impair the adhesion between composite resin and dentine and limit the penetration of disinfectants into dentinal tubules. This study aimed to compare the effects of 2% chlorhexidine (CHX), 980 nm diode laser, and Er:YAG laser as cavity disinfectants on dentine morphology, mineral content, and microleakage of composite restorations. MATERIALS AND

methodsForty extracted sound human primary molars were randomly assigned to four groups (n = 10): Group I (negative control, no disinfection), Group II (2% CHX application), Group III (980 nm diode laser, 1 W, continuous wave), and Group IV (Er:YAG laser, 1.2 W). Dentine morphology and restoration microleakage were examined via Scanning Electron Microscopy: (SEM), while mineral content was evaluated using Energy-Dispersive X-ray Spectroscopy (EDS).

resultsSEM analysis showed that CHX (Group II) left smear layer residues with narrowed tubules, while the diode laser (Group III) partially removed the smear layer. Er:YAG laser (Group IV) resulted in complete smear layer removal, wider tubules. EDS revealed significantly higher mineral content (Ca, P and Ca/P ratio)in Group IV compared to Groups II and group III (p < 0.001), with no significant difference between Groups II and III. Microleakage was highest in the control group and lowest in the Er:YAG group (p < 0.001).

conclusionThe Er:YAG laser showed enhanced outcomes in improving dentine morphology, increasing mineral content, and minimizing microleakage, making it the most effective disinfectant tested.

Identifiers

PMID41540055
PMCPMC12808308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.