Evidence map›Paper›PMID 41540047›Full record

ArticleNature communications2026

Structural mechanisms for inhibition and activation of human small-conductance Ca

Bao Ma, Di Wu, En Cao, Cheng Chi, Zhihao Wang, Zhanyi Xia, Long-Hua Sun, Bingxing Pan, Daohua Jiang, Wenhua Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Small-Conductance CaNeuroscience bulletin · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bao Ma *Jiangxi Institute of Respiratory Disease, The First Affiliated Hospital, and School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.
Di Wu *Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0003-2271-4963
En Cao *Jiangxi Institute of Respiratory Disease, The First Affiliated Hospital, and School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.
Cheng Chi *Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences at Weifang, Weifang, Shandong, China.
Zhihao WangJiangxi Institute of Respiratory Disease, The First Affiliated Hospital, and School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China.
Zhanyi XiaBeijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China.
Long-Hua SunThe Department of Respiratory and Critical Care Medicine and Jiangxi Provincial Key Laboratory of Respiratory Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, P.R. China.
Bingxing PanJiangxi Province Key Laboratory of Brain Science and Brain Health, Institute of Biomedical Innovation, Jiangxi Medical College, Nanchang University, Nanchang, China. panbingxing@ncu.edu.cn.ORCID http://orcid.org/0000-0001-6404-4019
Daohua JiangBeijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China. jiangdh@iphy.ac.cn.ORCID http://orcid.org/0000-0002-4397-5807
Wenhua ZhangJiangxi Institute of Respiratory Disease, The First Affiliated Hospital, and School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, China. whzhang@ncu.edu.cn.ORCID http://orcid.org/0000-0003-0230-9856

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32271272
6 · The paper itself

Abstract

The small-conductance calcium-activated potassium (SK1-3 or K

Indexed as

Small-Conductance Calcium-Activated Potassium Channels1-NaphthylamineApaminBinding SitesCalmodulinCryoelectron MicroscopyHEK293 CellsHumansImidazolesProtein BindingPyrazolesPyrimidines1-NaphthylamineApaminCalmodulincyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amineImidazolesKCNN2 protein, humanPyrazolesPyrimidines(R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamineSmall-Conductance Calcium-Activated Potassium Channels

Identifiers

PMID41540047
PMCPMC12917196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.