Evidence map›Paper›PMID 41539941›Full record

ArticleJournal of applied clinical medical physics2026

The Spinning Manny Indexed Overlay System for VMAT total body irradiation.

Lawrie Skinner, Eric Simiele, Zi Yang, Caressa Hui, Ignacio Romero, Michael Binkley, Richard Hoppe, Susan M Hiniker, Nataliya Kovalchuk

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Spinning Manny Indexed Overlay System for VMAT total body irradiation.Journal of applied clinical medical physics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lawrie SkinnerDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0001-7317-1642
Eric SimieleDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.
Zi YangDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.
Caressa HuiDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0002-3864-4720
Ignacio RomeroDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.
Michael BinkleyDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.
Richard HoppeDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.
Susan M HinikerDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.
Nataliya KovalchukDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0003-2619-7262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile modern intensity-modulated techniques for total body irradiation (TBI) offer superior organ sparing and improved dose coverage compared to conventional TBI, their complexity has limited widespread adoption. Specifically, when treating individuals with Volumetric Modulated Arc Therapy (VMAT-TBI), a transition between the head-first-supine (HFS) and feet-first-supine (FFS) orientations is typically required. This study introduces and evaluates the Spinning Manny Indexed Overlay System, an in-house developed rotational platform designed to streamline VMAT-TBI treatments.

methodsThe Spinning Manny platform is a carbon fiber overlay that indexes securely to the treatment table, allowing for accurate and reproducible patient rotation. Weight-bearing assessments, isocenter reproducibility evaluation, and dosimetric characterization through CT imaging and attenuation measurements were made. End-to-end testing was performed using anthropomorphic and solid water phantoms, with dosimetric verification using film and thermoluminescent dosimeters (TLDs). The system was clinically implemented for VMAT-TBI at Stanford University. Workflow efficiency and dose delivery accuracy were assessed through in vivo dosimetry and treatment plan comparisons.

resultsCommissioning tests confirmed the mechanical stability and dosimetric integrity of the Spinning Manny platform. Weight-bearing tests demonstrated support up to 159 kg, and isocenter reproducibility after rotation was within 1 mm. Attenuation at 6 MV was measured to be 4.3% and 1.3% at beam angles 30° and 90°, respectively, relative to the couch surface. For 10 MV, the attenuation was 3.4% and 1.0% at the same angles. Gamma passing rates in the end-to-end tests were 96.9% (3%/2 mm) for the lung regions and 92.6% (5%/3 mm) for the VMAT/AP/PA matchline. Clinical implementation across 136 patients (age range: 1-64 years old, height range: 83.6-197.3 cm) demonstrated efficient workflow integration, with 83% requiring HFS-to-FFS transitions. In vivo dosimetry confirmed accurate dose delivery at the matchline (96.1% ± 5.5% relative to prescription dose).

conclusionsThe Spinning Manny Indexed Overlay System effectively addresses a key logistical barrier in VMAT-TBI by enabling accurate and reproducible HFS-to-FFS transitions. Its mechanical stability, low attenuation, and high isocenter reproducibility support its clinical reliability, with successful implementation across patients of varying sizes and ages. By sharing this design, we aim to support the expansion and access of VMAT-TBI worldwide.

Indexed as

NeoplasmsPhantoms, ImagingRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedWhole-Body IrradiationHumansOrgans at RiskRadiotherapy DosageIMRT TBIrotational platformSpinning MannyVMAT TBI

Identifiers

PMID41539941
PMCPMC12807588

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.