Evidence map›Paper›PMID 41539117›Full record

Trial reportAddictive behaviors2026

Social media interventions and the moderation of baseline substance use: A secondary data analysis.

Devin C Tomlinson, Erin E Bonar, Autumn Rae Florimbio, Jason E Goldstick, Sean D Young, Maureen A Walton

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Devin C TomlinsonAddiction Center, Department of Psychiatry, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 16, Ann Arbor, MI, USA. Electronic address: tdevin@med.umich.edu.
Erin E BonarAddiction Center, Department of Psychiatry, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 16, Ann Arbor, MI, USA; Michigan Innovations in Addiction Care through Research & Education Program, Department of Psychiatry, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 16, Ann Arbor, MI, USA.
Autumn Rae FlorimbioAddiction Center, Department of Psychiatry, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 16, Ann Arbor, MI, USA.
Jason E GoldstickInjury Prevention Center, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 10, Ann Arbor, MI, USA; Department of Emergency Medicine, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI, USA; Department of Health Behavior and Health Education, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, USA.
Sean D YoungDepartment of Emergency Medicine, University of California Irvine, 1001 Health Sciences Road, Irvine, CA, USA.
Maureen A WaltonAddiction Center, Department of Psychiatry, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 16, Ann Arbor, MI, USA; Michigan Innovations in Addiction Care through Research & Education Program, Department of Psychiatry, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 16, Ann Arbor, MI, USA; Injury Prevention Center, University of Michigan, North Campus Research Complex, 2800 Plymouth Rd. Building 10, Ann Arbor, MI, USA.

Funding

MULTIDISCIPLINARY ALCOHOLISM RESEARCH TRAINING PROGRAMT32AA007477 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Maureen A. Walton · 1990 to 2026
$7.4M
Big Data Digital Outreach and Epidemiology Methods for HIV Care among Communities of ColorR01MD018548 · NIMHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI Sean Young · 2022 to 2026
$3.9M
Social Media Interventions to Reduce Alcohol Use among YouthR01AA024175 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WALTON, MAUREEN A · 2015 to 2019
$3.2M
Digital Device ID Targeting for Increasing Medications for Opioid Use Disorder: A Feasibility and Acceptability StudyR34DA054511 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI YOUNG, SEAN · 2021 to 2023
$707k
Optimizing an App-based Intervention for Sexual Minoritized Emerging Adults to Reduce Cannabis and Alcohol Co-useK23DA059484 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Autumn Rae H Florimbio · 2024 to 2026
$589k
NIAAA NIH HHS R01 AA024175NIAAA NIH HHS T32 AA007477NIDA NIH HHS K23 DA059484NIDA NIH HHS R34 DA054511NIMHD NIH HHS R01 MD018548
6 · The paper itself

Abstract

backgroundSubstance use is a significant public health problem with peak prevalence among adolescents and emerging adults (EAs). We present a secondary data analysis evaluating the moderating effect of baseline substance use on intervention outcomes from a randomized controlled trial of social media-delivered interventions for risky drinking among adolescents and EAs.

methodsAdolescents and EAs (ages 16 to 24; N = 955, 54.5 % female, 62.6 % white) were randomized to one of three conditions: social media intervention (SMI), social media intervention + incentives (SMI + I), and control. Using negative binomial regression models, we examined the extent to which baseline substance use (an index of the sum of frequencies of use for nine substances) moderated the effect of the SMI and SMI + I conditions on 3-, 6-, and 12-month substance use outcomes.

resultsThe interaction between baseline substance use and the SMI + I treatment condition, compared to control, was significant at 3-months (estimate = -0.024; p = 0.009), wherein individuals with higher baseline substance use had lower substance use at 3-months compared to the control condition. The interaction was not statistically significant at 6-months (p = 0.055) or 12-months (p = 0.782). The interaction with baseline substance use index was not significant for the SMI condition compared to the control condition.

conclusionsIndividuals in the SMI + I condition with higher baseline substance use had lower substance use at the 3-month follow-up compared to the control condition, suggesting that additional incentives for interaction benefited individuals in the short-term, particularly those with higher baseline substance use. Future work should explore the moderating role of subgroup characteristics to inform future tailoring of intervention content for substance use.

Indexed as

Social MediaSubstance-Related DisordersUnderage DrinkingAdolescentFemaleHumansMaleMotivationSecondary Data AnalysisTreatment Effect HeterogeneityYoung AdultAdolescentsEmerging adultsSocial media interventionsSubstance use

Identifiers

PMID41539117
PMCPMC12956035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.