Evidence map›Paper›PMID 41538587›Full record

ArticleJournal of applied oral science : revista FOB2026

Microstructures and mechanical characteristics of primary teeth affected by regional odontodysplasia.

Wenxiang Jiang, Minjian Shen, Jian Wang, Mengyao Bian, Haiyan Zheng, Zihuai Zhou, Ying Shi, Zhifang Wu

Abstract readCase Reports
In one paragraph

Article in Journal of applied oral science : revista FOB, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenxiang JiangEngineering Research Center for Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang University School of Medicine, School of Stomatology, Stomatology Hospital, Department of Pediatric Dentistry, Hangzhou, China.ORCID http://orcid.org/0009-0008-9371-5481
Minjian ShenNational Clinical Research Center for Child Health, Zhejiang University School of Medicine, Children's Hospital, Hangzhou Department of Stomatology, China.ORCID http://orcid.org/0000-0001-6335-6846
Jian WangEngineering Research Center for Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang University School of Medicine, School of Stomatology, Stomatology Hospital, Department of Pediatric Dentistry, Hangzhou, China.ORCID http://orcid.org/0000-0002-0961-7432
Mengyao BianEngineering Research Center for Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang University School of Medicine, School of Stomatology, Stomatology Hospital, Department of Pediatric Dentistry, Hangzhou, China.ORCID http://orcid.org/0000-0001-6102-8240
Haiyan ZhengEngineering Research Center for Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang University School of Medicine, School of Stomatology, Stomatology Hospital, Department of Prosthodontics, Hangzhou, China.ORCID http://orcid.org/0000-0001-7794-0242
Zihuai ZhouEngineering Research Center for Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang University School of Medicine, School of Stomatology, Stomatology Hospital, Department of Prosthodontics, Hangzhou, China.ORCID http://orcid.org/0000-0002-1685-6730
Ying ShiEngineering Research Center for Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang University School of Medicine, School of Stomatology, Stomatology Hospital, Department of Pediatric Dentistry, Hangzhou, China.ORCID http://orcid.org/0000-0003-3376-398X
Zhifang WuEngineering Research Center for Oral Biomaterials and Devices of Zhejiang Province, Cancer Center of Zhejiang University, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang University School of Medicine, School of Stomatology, Stomatology Hospital, Department of Pediatric Dentistry, Hangzhou, China.ORCID http://orcid.org/0000-0002-4122-4786

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigates the microstructural and mechanical characteristics of primary teeth affected by ROD. METHODOLOGY: A total of two ROD-affected primary teeth from two different cases underwent clinical examinations. In addition to control samples of caries-free retained primary teeth, the affected samples were examined using micro-computed tomography (micro-CT), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), and nanoindentation analysis.

resultsClinical findings revealed yellowish discoloration, rough surfaces, and root resorption on the affected teeth. Radiographs indicated hypocalcified enamel, widened pulp chambers, and delayed development of permanent teeth. Micro-CT showed affected teeth with thinner and uneven enamel, disordered dentin, and reduced mineral density. XRD analysis found reduced crystallinity. SEM and TEM analyses revealed hypoplastic and loosely packed enamel crystals, whereas dentin exhibited disorganized collagen fibrils and poorly mineralized crystals. EDS analysis showed a reduced calcium/phosphorus ratio and an increased magnesium/calcium ratio in the affected enamel. Nanoindentation tests found reduced hardness and elastic modulus in ROD-affected enamel compared with control teeth.

conclusionROD-affected primary teeth display significant microstructural abnormalities and compromised mechanical properties, underscoring the need for early intervention and long-term monitoring to prevent complications.

Indexed as

Dental EnamelTooth, DeciduousCase-Control StudiesChildDentinElastic ModulusFemaleHardnessHumansMaleMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionPhosphorusReference ValuesReproducibility of ResultsSpectrometry, X-Ray EmissionPhosphorus

Identifiers

PMID41538587
PMCPMC13124219

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.