Evidence map›Paper›PMID 41538521›Full record

SynthesisMemorias do Instituto Oswaldo Cruz2026

Trypanosomatid research in Brazil: a systematic analysis of regional and temporal trends.

Bárbara Marinho, Izabela Mamede, Júlia Raspante Martins, André Rodrigues, Ana Gabrielle Batista de Melo, Adalberto Sales Miranda-Junior, Alice Rios Neto, Amanda Carolina da Silva Nunes, Bruno Carvalho Resende, Dáfne Oliveira and 9 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Memorias do Instituto Oswaldo Cruz, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Bárbara MarinhoUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Izabela MamedeUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Júlia Raspante MartinsUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
André RodriguesUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Ana Gabrielle Batista de MeloUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Adalberto Sales Miranda-JuniorUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Alice Rios NetoUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Amanda Carolina da Silva NunesUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Bruno Carvalho ResendeUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Dáfne OliveiraUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Darlan Oliveira da SilvaUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Frederico Gabriel de Carvalho OliveiraUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Jéssica DuarteUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Lorrane Diniz de Carvalho SilvaUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Wesley Roger Rodrigues FerreiraUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Daniela De Laet-SouzaUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Andrea Mara MacedoUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.
Glória Regina FrancoUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Bioquímica e Imunologia, Laboratório de Genética Bioquímica, Belo Horizonte, MG, Brasil.ORCID 0000-0001-5245-2365
Carlos Renato Machado/ORCID 0000-0002-8724-3165

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTrypanosomatid infections such as Chagas disease (CD) and leishmaniasis remain major public-health concerns. Brazil has a long tradition in this field, yet a consolidated, country-level view of outputs, impact and collaboration patterns is useful to guide scientific policy.

objectivesTo characterise Brazilian scientific production on Trypanosoma cruzi, Leishmania and Trypanosoma brucei (2010-2021), describing temporal trends, regional contributions, collaboration networks and journal impact.

methodsWe performed a bibliometric analysis of PubMed records retrieved with Medical Subject Headings (MeSH) for each pathogen/disease pair, covering publications from 1 January 2010 to 31 December 2021 (search date: 21 July 2022). Data items included article type, year, journal, author affiliations (countries/institutions) and, for Brazil, the geographical region of the corresponding author. Descriptive statistics and visualisations were generated in R.

findingsFrom 21,713 records, 6,478 were affiliated to Brazil. Brazil contributed a substantial share of the global literature, particularly for T. cruzi (≈40%) and Leishmania (≈30%). Within Brazil, output increased over time with growing participation from the north and northeast, alongside expanding inter-institutional and international collaborations. Most publications appeared in higher-impact journals (Q1/Q2), with recent gains in Q1 outputs in historically under-represented regions. Original research predominated over reviews across the period. MAIN

conclusionsBrazilian trypanosomatid research shows sustained growth, increasing regional dispersion and rising international engagement, with a strong presence in high-impact journals. Continued support for collaborative networks and equitable funding across regions could further enhance national and global impact.

Indexed as

BibliometricsBiomedical ResearchBrazilChagas DiseaseHumansPeriodicals as Topic

Identifiers

PMID41538521
PMCPMC12795327

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.