Evidence map›Paper›PMID 41538229›Full record

Trial reportExperimental and clinical psychopharmacology2026

Community Reinforcement and Family Training (CRAFT) goes digital: Randomized pilot trial for families of individuals with opioid use problems.

Jane P Macky, Kimberly C Kirby, Ben G Fitzpatrick, Shelby Goodwin, Mary Milnamow, Jaime Kishpaugh, Erica J Lubetkin, Michelle L Kuecker, Benjamin Bearnot, Robert J Meyers and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental and clinical psychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jane P MackyWe the Village, Inc.ORCID 0000-0002-2241-6918
Kimberly C KirbyWe the Village, Inc.
Ben G FitzpatrickTempest Technologies.
Shelby GoodwinRowan University, Department of Psychology.ORCID 0000-0003-2863-0007
Mary MilnamowPublic Health Management Corporation.
Jaime KishpaughPublic Health Management Corporation.
Erica J LubetkinWe the Village, Inc.
Michelle L KueckerWe the Village, Inc.
Benjamin BearnotWe the Village, Inc.
Robert J MeyersWe the Village, Inc.
Calum J HandleyWe the Village, Inc.

Funding

SBIR PHASE 1: SCALABLE DIGITAL DELIVERY OFEVIDENCE-BASED TRAINING FOR FAMILY TO MAXIMIZETREATMENT ADMISSION RATES OF OPIOID USE DISORDER INLOVED ONES.75N95019C00070 · NIDA · WE THE VILLAGE, INC. · PI MACKY, JANE · 2019 to 2020
$280k
National Institutes of Health; National Institute on Drug Abuse Small Business Innovation ResearchNIDA NIH HHS 75N95019C00070
6 · The paper itself

Abstract

Community Reinforcement and Family Training (CRAFT) for concerned significant others (CSOs) of individuals with substance use problems (IP) is an efficacious in-person intervention warranting broader dissemination. However, previous web-based delivery studies have not achieved the increases in IP treatment entry seen with in-person studies. We developed two online CRAFT programs closely aligned with the in-person CRAFT protocol and pilot tested their efficacy and feasibility. We block randomized 45 CSOs (15/arm) of IPs with opioid use problems to receive 12 weeks of web-based peer support (PEER) or weekly web-based CRAFT modules with videoconference coaching either in groups (CRAFT-G) or individually (CRAFT-I). Though not statistically significant, more CSOs reported new IP treatment entry in CRAFT-G (76.9%; OR = 5.00, 95% CI [0.03, 3.41], p = .056) and CRAFT-I (72.7%, OR = 4.01, 95% CI [-0.23, 3.20], p = .106) compared to PEER (40.0%), and more CRAFT-G participants reported their IP was in medication treatment at 12 weeks compared to PEER (76.9% vs. 40.0%, OR = 5.00, 95% CI [0.19, 0.98], p = .11). CRAFT-G had significantly improved physical health (p = .025) and mood (p = .015), and both CRAFT-G (p = .018) and CRAFT-I (p = .012) showed increased relationship satisfaction compared to PEER. CSO engagement was similar across conditions. Results must be interpreted cautiously as the study was exploratory and small, and some results were not statistically significant. This pilot study is the first to suggest that online CRAFT programs have the potential to replicate in-person effects, possibly because it did not shorten or significantly alter the in-person protocol when adapting it to a digital format. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

FamilyFamily TherapyOpioid-Related DisordersAdultFemaleHumansInternet-Based InterventionMaleMiddle AgedPeer GroupPilot ProjectsReinforcement, PsychologyVideoconferencing

Identifiers

PMID41538229
PMCPMC12818555

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.