Evidence map›Paper›PMID 41538094›Full record

ArticleVeterinary research communications2026

Molecular identification and genetic diversity of Echinococcus granulosus sensu stricto in livestock from Qinghai lake on the Qinghai-Tibetan plateau.

Jun He, Guoyan Zhou, Fan Zhang, Hongrun Ge, Ao Chen, Ru Meng, Zhihong Guo, Yijuan Ma, Yong Fu

Abstract read
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In one paragraph

Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jun He *Academy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China.
Guoyan Zhou *Academy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China.
Fan ZhangAcademy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China.
Hongrun GeAcademy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China.
Ao ChenAcademy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China.
Ru MengXining Animal Disease Control Center, Xining, 810016, China.
Zhihong GuoAcademy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China.
Yijuan MaAcademy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China. mayijuan@qhu.edu.cn.
Yong FuAcademy of Animal Sciences and Veterinary Medicine, Qinghai Provincial Key Laboratory of Pathogen Diagnosis for Animal Diseases and Green Technical Research for Prevention and Control, Qinghai University, Xining, 810016, China.

Funding

Key R&D and Conversion Plan of Qinghai Province (2025- QY-227)National Natural Science Foundation of China (32160840)Open Project of State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases (RCGHCRB202506)
6 · The paper itself

Abstract

Echinococcus granulosus sensu stricto (G1 genotype), the predominant causative agent of zoonotic cystic echinococcosis, continues to jeopardize public health across the pastoral ecosystems of the Qinghai-Tibetan Plateau. Here, we provide a novel molecular genetic evidence from the Qinghai Lake by investigating hydatid cysts in two key livestock species sheep and yaks. Through an innovative dual-marker strategy targeting mitochondrial Cytochrome c oxidase subunit 1 (cox1) and NADH dehydrogenase subunit 1 (nad1) genes, we conducted PCR amplification and haplotype analysis, combined with maximum likelihood (ML)-based phylogenetic reconstruction and divergence time estimation. The results demonstrated that all 13 positive samples belonged to the Echinococcus granulosus genotype 1 of E. granulosus s. s. and reveal a pivotal Miocene-Pliocene divergence event (5.8 ± 0.5 million years ago) within Echinococcus spp., establishing critical evolutionary benchmarks. This study not only provides updated epidemiological data on echinococcosis in the Qinghai Lake, but more importantly, deliver critical molecular evidence for precision control of zoonotic diseases in high-altitude pastoral ecosystems.

Indexed as

Cattle DiseasesEchinococcosisEchinococcus granulosusGenetic VariationSheep DiseasesAnimalsCattleElectron Transport Complex IVHaplotypesLakesNADH DehydrogenasePhylogenySheepTibetElectron Transport Complex IVNADH DehydrogenaseEchinococcus granulosus sensu strictoMolecular epidemiologyQinghai lakeQinghai-Tibetan plateauZoonotic cystic echinococcosis

Identifiers

PMID41538094

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.