Evidence map›Paper›PMID 41538074›Full record

Observational studyArchives of gynecology and obstetrics2026

Abnormal fasting glucose levels in the diagnosis of GDM may be associated with adverse pregnancy outcomes.

Lin Wang, Minghui Qin, George Q Chen, Yue Wang, Dengxin Zhang, Qi Chen, Ying Gu, Min Zhao

Abstract readObservational Study
In one paragraph

Observational study in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lin WangDepartment of Gynaecology, Wuxi School of Medicine, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China.
Minghui QinDepartment of Gynaecology, Wuxi School of Medicine, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China.
George Q ChenRoyal Liverpool University Hospital, Liverpool, UK.
Yue WangDepartment of Gynaecology, Wuxi School of Medicine, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China.
Dengxin ZhangDepartment of Anesthesia, Wuxi School of Medicine, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China.
Qi ChenDepartment of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Ying GuDepartment of Obstetrics, Wuxi School of Medicine, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China. guyingwxfy@163.com.
Min ZhaoDepartment of Gynaecology, Wuxi School of Medicine, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China. zmdoc2002@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational Diabetes Mellitus (GDM) presents significant risks to both maternal and foetal health during pregnancy. PURPOSE: This observational study aimed to investigate the association between clinical parameters and adverse pregnancy outcomes in women with GDM.

methodsA cohort of 2174 GDM-diagnosed women was analysed, with 1705 experiencing no adverse outcomes and 469 developing complications such as preeclampsia, large for gestational age (LGA) infants, preterm birth, and shoulder dystocia. Clinical data, including maternal age, glucose levels, gestational age, body mass index (BMI), and treatment methods, were collected and analysed.

resultsAdvanced maternal age, higher parity, increased weekly weight gain, and abnormal fasting glucose levels were associated with adverse pregnancy outcomes in women with GDM. In particular, early onset of GDM, elevated weekly weight gain, and abnormal fasting glucose levels were linked to an increased risk of developing preeclampsia and delivering LGA infants. However, no significant associations were found regarding shoulder dystocia. Furthermore, maternal age and weekly weight gain were identified as risk factors for preterm birth.

conclusionThis study shows that in addition to well-known risk factors, abnormal fasting glucose levels are significantly linked to developing adverse pregnancy outcomes in women with GDM. Our data suggested that close monitoring of fasting glucose levels and controlling weight gain may significantly reduce the risk of adverse outcomes in pregnancies complicated by GDM.

Indexed as

Blood GlucoseDiabetes, GestationalPregnancy OutcomeAdultBody Mass IndexFastingFemaleFetal MacrosomiaGestational AgeGestational Weight GainHumansInfant, NewbornMaternal AgeParityPre-EclampsiaPregnancyBlood GlucoseAdverse pregnancy outcomesGestational diabetes mellitusOGTTOnset of GDM

Identifiers

PMID41538074
PMCPMC12808146

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.