Evidence map›Paper›PMID 41537768›Full record

ArticleThe Permanente journal2026

Value-Based Management of Pediatric Acute-Onset OCD: A Case Consistent With Possible Pediatric Acute-Onset Neuropsychiatric Syndrome.

Eric Kazangian, Christian Alan Botz-Zapp, Jami Wang, Vicky Ho, Emily Fu

Abstract read
In one paragraph

Article in The Permanente journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric KazangianKaiser Permanente Southern California Psychiatry Residency Program, Kaiser Permanente Fontana Medical Center, Fontana, CA, USA.ORCID 0009-0008-0519-2407
Christian Alan Botz-ZappDepartment of Psychiatry, Psychiatry Residency Training Program, University of California San Diego, San Diego, CA, USA.ORCID 0000-0002-7428-6238
Jami WangKaiser Permanente Southern California Psychiatry Residency Program, Kaiser Permanente Fontana Medical Center, Fontana, CA, USA.ORCID 0000-0002-6814-1817
Vicky HoKaiser Permanente Southern California Psychiatry Residency Program, Kaiser Permanente Fontana Medical Center, Fontana, CA, USA.ORCID 0009-0000-0717-647X
Emily FuKaiser Permanente Southern California Psychiatry Residency Program, Kaiser Permanente Fontana Medical Center, Fontana, CA, USA.ORCID 0009-0001-2354-4217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case highlighted a value-based approach to abrupt-onset obsessive-compulsive disorder (OCD) consistent with a possible pediatric acute-onset neuropsychiatric syndrome (PANS) presentation, where timely intervention facilitated recovery while avoiding unnecessary and costly levels of care. The authors have described a 14-year-old male who developed sudden, severe OCD symptoms following influenza A infection. His presentation included functional decline, poor insight, and complex family dynamics. Traditional pediatric OCD was considered but deemed less likely due to the abrupt onset, absence of family history, and persistence of symptoms postinfection. Minimal treatment engagement and refusal of medication necessitated an extended involuntary hold and court-approved pharmacotherapy due to illness severity and medical complications. With initiation of fluoxetine during inpatient treatment, the patient stabilized and transitioned to intensive outpatient therapy. This case underscored the importance of recognizing PANS as a potential diagnostic framework, ensuring appropriate evaluation of underlying causes, and implementing timely, decisive treatment. As antibody testing, including central nervous system and cerebrospinal fluid autoantibody testing, were not obtained, the diagnostic certainty was best characterized as a possible PANS presentation. Lastly, this case illustrated a value-based care model, emphasizing efficient diagnostic testing, judicious use of higher levels of care, and coordinated transitions that reduced cost without compromising outcomes.

Indexed as

InfluenzaObsessive Compulsive DisorderPANS

Identifiers

PMID41537768
PMCPMC12989769

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.