Evidence map›Paper›PMID 41537597›Full record

ArticleJournal of virology2026

Impact of mutations affecting 4'-fluorouridine susceptibility on fitness and treatment outcomes for Venezuelan equine encephalitis virus.

Jenny Wong, Tahirah Moore, Devin Lewis, Carolin M Lieber, Dariia Vyshenska, Elizabeth B Sobolik, Sarah Zimmermann, George R Painter, Richard K Plemper, Alexander L Greninger and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jenny WongCenter for Translational Antiviral Research, Georgia State University Institute for Biomedical Sciences, Atlanta, Georgia, USA.
Tahirah MooreCenter for Translational Antiviral Research, Georgia State University Institute for Biomedical Sciences, Atlanta, Georgia, USA.
Devin LewisCenter for Translational Antiviral Research, Georgia State University Institute for Biomedical Sciences, Atlanta, Georgia, USA.
Carolin M LieberCenter for Translational Antiviral Research, Georgia State University Institute for Biomedical Sciences, Atlanta, Georgia, USA.
Dariia VyshenskaVirology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, USA.
Elizabeth B SobolikVirology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, USA.
Sarah ZimmermannCenter for Translational Antiviral Research, Georgia State University Institute for Biomedical Sciences, Atlanta, Georgia, USA.
George R PainterEmory Institute for Drug Development, Emory University, Atlanta, Georgia, USA.
Richard K PlemperCenter for Translational Antiviral Research, Georgia State University Institute for Biomedical Sciences, Atlanta, Georgia, USA.
Alexander L GreningerVirology Division, Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington, USA.ORCID 0000-0002-7443-0527
Robert M CoxCenter for Translational Antiviral Research, Georgia State University Institute for Biomedical Sciences, Atlanta, Georgia, USA.ORCID 0000-0003-0620-1674

Funding

Georgia State University Research Initiation Grant (RIG)
6 · The paper itself

Abstract

Venezuelan equine encephalitis virus (VEEV) is a prototypical encephalitic alphavirus. Members of the

Indexed as

Antiviral AgentsDrug Resistance, ViralEncephalitis Virus, Venezuelan EquineEncephalomyelitis, Venezuelan EquineMutationUridineAnimalsCell LineChlorocebus aethiopsFemaleHumansMiceTreatment OutcomeVero CellsVirus ReplicationAntiviral AgentsUridine4′-fluorouridineantiviralsusceptibilityVEEV

Identifiers

PMID41537597
PMCPMC12911897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.