Evidence map›Paper›PMID 41537591›Full record

ArticleAntimicrobial agents and chemotherapy2026

Comparative effectiveness of two antimicrobial regimens for the treatment of pan-drug-resistant

Konstantinos Pontikis, Ilias Karaiskos, Aikaterini Sakagianni, Eleni Mouloudi, Evdoxia Tsigou, Aikaterini Gkoufa, Sofia Michelidou, Kristina Mouratidou, Alexandra Gavala, Christina Routsi and 11 more

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Antimicrobial regimens for the treatment of pan-drug-resistantAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Konstantinos Pontikis *Chest Diseases Hospital 'I Sotiria', Intensive Care Unit 1st Department of Pulmonology, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-3533-9608
Ilias Karaiskos *1st Department of Internal Medicine - Infectious Diseases, Hygeia General Hospital, Athens, Greece.
Aikaterini SakagianniIntensive Care Unit, Sismanogleio General Hospital of Attica, Athens, Greece.ORCID 0000-0002-3199-9158
Eleni MouloudiIntensive Care Unit, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece.ORCID 0000-0003-0079-2012
Evdoxia TsigouIntensive Care Unit, General and Oncologic Hospital of Kifisia 'Oi Agioi Anargyroi', Athens, Greece.
Aikaterini Gkoufa1st Department of Medicine, School of Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0001-5644-8208
Sofia MichelidouIntensive Care Unit, Sismanogleio General Hospital of Attica, Athens, Greece.
Kristina MouratidouIntensive Care Unit, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece.ORCID 0009-0007-8657-2032
Alexandra GavalaIntensive Care Unit, General and Oncologic Hospital of Kifisia 'Oi Agioi Anargyroi', Athens, Greece.
Christina RoutsiEvangelismos General Hospital 1st Department of Intensive Care Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-5871-1361
Stamatis KarakonstantisInternal Medicine Department, University Hospital of Heraklion, Heraklion, Greece.ORCID 0000-0002-2643-3184
Stavroula MichaleaIntensive Care Unit, Korgialenio-Mpenakio General Hospital, Athens, Greece.
Sevasti AmpeliotiChest Diseases Hospital 'I Sotiria', Intensive Care Unit 1st Department of Pulmonology, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0003-1235-0182
Theodora KatsarouIntensive Care Unit, Chest Diseases Hospital 'I Sotiria', Athens, Greece.
Athanasios PapathanasiouIntensive Care Unit, University Hospital of Ioannina, Ioannina, Greece.
Maria Pirounaki2nd Department of Internal Medicine, School of Medicine, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Charalambos AnastogiannisIntensive Care Unit, Aghios Andreas Hospital, Patras, Greece.
Antonia KoutsoukouChest Diseases Hospital 'I Sotiria', Intensive Care Unit 1st Department of Pulmonology, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-1536-3205
Helen Giamarellou1st Department of Internal Medicine - Infectious Diseases, Hygeia General Hospital, Athens, Greece.ORCID 0000-0002-7387-5065
George L Daikos2nd Department of Internal Medicine, Mitera General Hospital, Athens, Greece.ORCID 0000-0001-5365-4874
DESPAIR Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pan-drug-resistant

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsAgedAmpicillinBacteremiaColistinDrug Resistance, Multiple, BacterialFemaleHumansMaleMeropenemMicrobial Sensitivity TestsMiddle AgedMinocyclineRetrospective StudiesAmpicillinAnti-Bacterial AgentsColistinMeropenemMinocyclineSulbactamsultamicillinThienamycinsTigecyclineantimicrobial resistancecolistinmeropenempan-drug-resistant Acinetobacter baumanniitigecyclinetriple antibiotic therapy

Identifiers

PMID41537591
PMCPMC12959155

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.