Evidence map›Paper›PMID 41537191›Full record

ArticleDatabase : the journal of biological databases and curation2026

H-SPAR DB: human spaceflight platform for analysis and research-an integrative omics database for space health.

Marios Tomazou, Marilena M Bourdakou, Eleni Nicolaidou, Grigoris Georgiou, Kyriaki Savva, Efi Athieniti, Styliana Menelaou, Sotiroula Afxenti, George M Spyrou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Database : the journal of biological databases and curation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marios TomazouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
Marilena M BourdakouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0001-8075-0634
Eleni NicolaidouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
Grigoris GeorgiouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
Kyriaki SavvaBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
Efi AthienitiBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
Styliana MenelaouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
Sotiroula AfxentiBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.
George M SpyrouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, 2371 Nicosia, Cyprus.ORCID 0000-0002-2470-3363

Funding

Research and Innovation Foundation
6 · The paper itself

Abstract

H-SPAR DB is a comprehensive database designed to support space health research by providing a unified platform for data integration, analysis, and interpretation. The database simplifies the complex workflows associated with spaceflight-related biology studies by combining curated molecular lists, transcriptomic datasets from NASA's GeneLab, and user-uploaded data into a streamlined, user-friendly interface. H-SPAR DB enables researchers to perform differential expression analysis, set operations, and association analyses while also generating integrative knowledge graphs around a space-related biological theme. The platform reduces the time required for data gathering and processing by offering a single platform for data exploration, analysis, and visualization. By integrating interactive visualizations and data tables, H-SPAR DB facilitates the interpretation of results, ultimately enhancing the efficiency of space biology research and fostering discoveries that address human health challenges in space. Researchers can access H-SPAR DB freely at https://bioinformatics.cing.ac.cy/H-SPARDB/ without login or other requirements.

Indexed as

Databases, FactualDatabases, GeneticSpace FlightBiocurationHumansUser-Computer Interface

Identifiers

PMID41537191
PMCPMC12805116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.